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Anthropic IPO at Risk, Meta’s Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails

All-In Podcast2026-09-2601:34:23

English is primary. Chinese is a reading aid. Timestamps come from the official timed captions.

章节目录
  1. 00:00:00Bestie Intros: Favorite All-In Summit moments
  2. 00:03:54Reacting to AI chaos: Liability, competition, and rebranding frontier "labs"
  3. 00:20:03Non-frontier performance and cost: What this means for frontier companies
  4. 00:29:22Anthropic and OpenAI postpone IPOs: liquidity risk and open source pressure
  5. 00:53:11Political reactions to "Pacing the Frontier": Bernie's AI ban, Trump, Bessent, Obama
  6. 01:07:58Meta launches Muse, AI "alignment," Oracle's Force Majeure
  7. 01:27:13Anthropic’s bio research and "wet lab" in SF
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00:00:00

Bestie Intros: Favorite All-In Summit moments

Jason Calacanis

Welcome back to episode 290 of the number one podcast in the world. It's the All-In podcast. With me again, it's the core 4. David Friedberg is here. Chamath Palihapitiya and David Sacks are calling in. I am your host, Jason Calacanis, and we have a full docket today.

I'd be remiss if I didn't ask everybody for their fondest memories of the 5th annual All-In Summit, produced by Mr. David Friedberg. David, do you have any thoughts? How do you rate your performance as executive producer of the All-In Summit?

中文

欢迎回到“世界第一播客”All-In 的第 290 期。本期 Core Four 再次到齐:David Friedberg 在现场,Chamath Palihapitiya 和 David Sacks 远程连线,Jason Calacanis 主持。议题很多,但 Jason 先请大家回忆由 Friedberg 制作的第五届 All-In Summit 中最喜欢的时刻,并让他评价自己的执行制作表现。

David Friedberg

You know what we didn't do? What we forgot to do at the end of day 2 was give a big shout-out to our production team—to Kimber, Lisa, and Nick. I thought we should have brought them out, but I just want to give them a big shout-out.

The team backstage absolutely crushed it, as always, this year. And then I had a great time. Actually, my favorite part is going to Universal Studios. You just get to have a good time. It's great—just great.

中文

Friedberg 说峰会第二天结束时漏了一件事:应该把 Kimber、Lisa 和 Nick 等制作团队请上台接受掌声,因此现在特别向他们致谢。后台团队今年依然表现出色;他自己也玩得很开心,尤其喜欢去 Universal Studios,那让人可以单纯放松享受。

TIMESTAMP_UNVERIFIEDJason Calacanis

Bring them out for the standing ovation.

I'm reliving my childhood. Shabbat with no trauma.

By the way, shout-out to our friends at Dongi. I got one of those coffee machines that we had at the event. I put it in my kitchen.

You know what I got? I don't know if you guys saw, but there was a water machine in the VIP area. Well, that is a zero-plastic water machine. It goes through super filtration. No microplastics in the water. I have one now in our office. Thank you very much to them. I appreciate it. Amazing company.

Sacks, do you have a favorite moment from the show?

中文

Jason 说应该请制作团队上台接受全场起立鼓掌,又笑称自己像在重温童年。他还感谢活动上的合作伙伴:自己把现场的咖啡机搬进了厨房,也在办公室装了一台 VIP 区使用的零塑料净水机,通过深度过滤去除水中的微塑料。随后他问 Sacks 最喜欢峰会中的哪个时刻。

David Sacks

I think the highlight of the show, the thing that we'll remember for a long time, was the president calling in during Jensen's talk. Jensen's overall content and demeanor really helped calm down this national panic over AI. It felt like we were at the center of this national conversation.

I think it happened very organically. You remember, there's basically been this campaign for the last few weeks leading into the summit to convince everyone that humanity was going to go extinct unless we did exactly what the Democrats wanted and stopped all AI development. Then Satya came out and kind of calmed everyone down, and Jensen did the same thing. The president called in and did what he does best, which is seize total control of the narrative that I'm sure these doomer groups had been carefully planning for weeks, and kind of thwarted that whole operation.

中文

Sacks 认为最令人难忘的是总统在 Jensen 演讲期间打来电话。Jensen 的内容与表达帮助缓解了全国对 AI 的恐慌,让峰会仿佛处在全国讨论的中心。这一切非常自然:峰会前几周,有人不断宣称若不按民主党的主张停止所有 AI 开发,人类就会灭亡;Satya 和 Jensen 先后让局面降温,总统又打来电话,凭借自己掌控叙事的能力打乱了这些 doomer 团体筹划多时的议程。

Jason Calacanis

Nerds, enough. Get back to work. You have a superintelligent Trump. Intelligence is now the term. We're going to call it Trump intelligence going forward.

But I think you make a good point. A lot of people wanted to know, Friedberg, if this was planned. Was President Trump's call planned? Friedberg, take us behind the scenes.

中文

Jason 调侃道,nerds 应该停止恐慌、回去工作,并把“superintelligent Trump”称为新的“Trump intelligence”。他随后问 Friedberg,总统打来电话是不是事先安排好的,请他介绍幕后情况。

David Friedberg

Basically, Jensen was connecting with him right backstage and said, “Hey, call me back.” Then he called him while he was onstage. There was some texting going on.

中文

Friedberg 说,Jensen 当时在后台与总统联系,让对方回电话;总统恰好在 Jensen 上台时打了回来,期间双方也发过一些短信。

Jason Calacanis

Yeah, it was completely spontaneous. It was not a planned thing where Jensen was like, “Hey, let's do a whole thing.” It was pretty amazing to have the conversation that Jensen was waiting for from the president happen live. Clearly, this was the topic du jour in D.C., as well as in the news and the media, and it was amazing to see it all happen onstage with us.

Just to be clear, I thought it was a bit. I was like, “Well, put him on speakerphone.” Jensen says to me, “How do you do that?” I just handed him—I always keep an extra mic there in case somebody's mic goes out—and said, “Put him on speakerphone. Put the microphone there.”

President Trump, the funniest president in history, the funniest politician in history—did you notice, Sacks, that he drops a one-liner through a speakerphone perfectly?

Jensen makes the greatest chips. Everybody tries to reverse-engineer them. Impossible. Impossible. But he can't figure out how to press the speakerphone button. I was just like, “How does he do it? How does he do it?” He just drops the perfect line.

But, Chamath, in all seriousness, the nerds were losing their minds last week, and the adults came. Daddy came. Elon came. Jensen came. All the adults in the room came and just said, “Listen, if you have software that's defective and not ready to put in the world, maybe don't put it in the world and make it a little bit—as you like to say—less brittle.” So, your thoughts on where we are in this national discussion, which went from “slow down” to maybe just release non-brittle, resilient software?

中文

Jason 强调这完全是临场发生的,并非 Jensen 预先设计的桥段。总统期待已久的谈话就这样在现场展开,而 AI 又正是华盛顿和媒体的热门议题,整个过程很特别。Jason 起初还以为这是表演,于是让 Jensen 打开免提;Jensen竟然不知道怎么操作,他只好递上一支备用麦克风。Jason 笑称 Trump 隔着免提也能精准抛出一句笑话,而 Jensen 能造出全世界都无法逆向复制的顶级芯片,却不会按免提键。随后他转向 Chamath:上周 Elon、Jensen 等“成年人”都出来说,若软件有缺陷、还没准备好,就先别发布,把它做得更稳健;他想知道全国讨论为何从“放慢 AI”转向“发布不脆弱、具有韧性的软件”。

00:03:54

Reacting to AI chaos: Liability, competition, and rebranding frontier "labs"

Chamath Palihapitiya

I think there was this classification that happened last week between up-and-coming organizations that want to call themselves labs but are, in fact, companies that have P&Ls and shareholders and have to abide by the same rules that everybody else does, and the sophisticated companies that have lived under scrutiny for many decades and have learned the hard way the process of making things robust and the cost of making things not robust.

So what do I mean? On the one side, you saw—in many ways, it's like, “Curious times create curious bedfellows.” You have the cohort of Satya, Jensen, Sacks, Zuck, Elon, the president, and Lina Khan. We have product-liability laws in the United States. They're meant to prevent companies from doing things that they're not supposed to do, especially if they know that those things could be harmful.

中文

Chamath 认为上周出现了一次清晰分类:一边是自称“lab”的新兴组织,但它们实际上拥有 P&L、股东,也应遵守与其他企业相同的规则;另一边是经历几十年监督的成熟公司,它们已经从代价中学会如何让产品稳健。他说局势让 Satya、Jensen、Sacks、Zuck、Elon、总统乃至 Lina Khan 站到了相近立场。美国本来就有产品责任法,用来阻止企业明知可能造成伤害仍做不该做的事。

TIMESTAMP_UNVERIFIEDDavid Sacks

Strange fellows indeed.

中文

Sacks 接话说,这确实是一群很特别的同路人。

Chamath Palihapitiya

On the other side, it's folks making the thing who were, I think, being a little naive and basically saying, “We're not a company. We're a lab. Protect us.” I think the mature response is, “You should have internal controls, and you should robustly test things.”

What Zuck said earlier and what Elon has said in the past is that we're just under a lot of scrutiny. When things aren't perfect, we slow things down. Elon has done that with FSD. He could have been at FSD 3 or 4 years ago, but he has publicly stated, “We can't afford it, because every accident that Tesla incurs is magnified 1,000 times more than what any other company would incur, and so we just have to go slower.”

Zuck last week said, “We were about to roll out Muse,” which looks like one of the most successful product launches in recent memory and has huge implications, actually, which we should talk about. He had to slow-roll it. He and Alexandr Wang, who I was talking to last night, had to slow-roll it for a couple of months to get it perfect.

It's all within your control. It's just what you choose to do. I think that was the most interesting observation. We have to stop calling these companies labs. They're companies, and we have to judge them by the same standards, including product liability.

中文

Chamath 说另一边的产品制造者显得有些天真,仿佛在说“我们不是公司而是实验室,所以请保护我们”。成熟做法应该是建立内部控制并充分测试。Zuck 和 Elon 都说过,他们长期处在严格审视下,产品不够完善就会放慢。Elon 原本可能早三四年推出 FSD,但 Tesla 的每起事故都会被放大千倍,只能更加谨慎。Zuck 的 Muse 看起来会成为近年来最成功的产品发布之一,但他和 Alexandr Wang 仍推迟数月把它完善。是否稳健都在公司自己控制之中,因此这些机构不应再被称为 labs,而应以公司标准和产品责任来评价。

Jason Calacanis

Yeah, and there was a lot of coverage of this moment, Sacks. Interestingly, some of the fake-news media were like, “On a popular podcast,” and then they played the clip, but they're just afraid to say the name of the podcast. Pretty hilarious.

中文

Jason 说这一观点获得了很多报道,但有些他所谓的“假新闻媒体”播放节目片段时只说“某热门播客”,却不敢直接说出 All-In 的名字,令人发笑。

David Sacks

I think Chamath is getting us into the first topic here already, which is whether we're going to have individual responsibility as our North Star or some sort of collective action. The thing that always works the best is individual responsibility, whether it's at the level of individuals or companies. The relevant decision to make in every case is, “Should we ship this product?”—not, “Can we get the whole world to agree?”

The problem with talking about these collectivized approaches is that they deflect accountability away from the actual decision-maker. I think people sort of feel this. This week, you had Dario and Sam go to the United Nations and say we need some sort of global AI governance. It kind of reminds me of the billionaires who fly to Davos in their private jets and then rail against climate change. There's something fundamentally unrealistic and out of touch about it.

中文

Sacks 认为首个核心问题是:以个人责任为准则,还是依赖集体行动。无论个人还是公司,最有效的始终是各自承担责任;真正需要回答的是“我们该不该发布这个产品”,而不是“能否让全世界先达成一致”。集体治理会把责任从实际决策者身上移开。Dario 和 Sam 本周到联合国呼吁全球 AI 治理,让他想起坐私人飞机去 Davos、却批评气候变化的亿万富翁,既不现实又与普通世界脱节。

Jason Calacanis

Hypocritical.

David Sacks

Hypocritical. And it's like, guys, look, what we need is for you to make smart decisions about what to release. If a product is unsafe—which is to say, it's unreliable or behaves unpredictably—then don't release it. Stop looking to some sort of global governance as the answer.

If you guys don't get this decision right, it's not going to matter what the United Nations does. By the time the United Nations agrees on anything, we're going to be much further along in this whole journey. There's something just very weird about the way that the principal actors in this keep talking, because it really feels like they're trying to push off the responsibility.

中文

Jason 用“虚伪”概括,Sacks 表示同意。他说企业需要对发布作出明智决定:产品若不安全,也就是不可靠或行为不可预测,就不要发布,不要把全球治理当成答案。如果企业自己的决定做错,联合国做什么都没用;等联合国达成共识时,AI 早已进展很远。当前主要参与者的表态显得奇怪,像是在把自身责任推给别人。

Jason Calacanis

Well, there's a theory going around here, and I think it is worth us discussing here, that the Frontier Labs are covertly—

David Sacks

They're companies.

Jason Calacanis

They're companies. Yes. Let me just finish the—

David Sacks

No, no, no, but you made a really good point that I want to make sure we don't miss.

Jason Calacanis

Okay.

David Sacks

They are corporations.

中文

Jason 正要介绍一项关于 Frontier Labs 的理论,Sacks 多次打断并坚持纠正:它们是公司,是 corporations,而不是 labs。Jason 同意并让他把这个重要区别说清楚。

Jason Calacanis

Yes. Yes. And when you call them labs, they sound like nonprofit entities, and that's not true.

The corporations making these products are looking for President Trump to specifically give them what the internet companies had with Section 230, which is to shield them from liability. There is a consideration inside the Trump administration—the 47th administration—that maybe there could be some leverage put on these companies: They would give 10% of their equity to the sovereign wealth fund of the United States, and then that would result in them being given some pass when it comes to their liability.

That's an insane thing to do. It's like giving some plane company that gives 10% of its equity to the U.S. government the ability not to be responsible for its planes falling out of the sky.

But what is your thought on that conspiracy theory? I'm sure you've heard it, Sacks—that they're looking for—

中文

Jason 说“lab”会让人误以为它们是非营利机构,事实并非如此。据称这些公司希望 Trump 给予类似互联网公司 Section 230 的保护,免除产品责任;还有传闻说,它们可以把 10% 股权交给美国主权财富基金,以换取责任豁免。Jason 认为这极其荒谬,就像飞机制造商给政府 10% 股权后,飞机坠毁也不用负责。他请 Sacks 评价这些公司是否在谋求这种安排。

David Sacks

You're making it sound like this is the idea of the Trump administration. That's not true.

Jason Calacanis

No, not the Trump administration. This is what the frontier labs and corporations are pitching to them, and the rumor is that there might be some people who are open to that in the administration. Again, this is all a back channel.

中文

Sacks 先指出 Jason 的说法听起来像这是 Trump 政府的主意,事实不是。Jason 澄清,这是 frontier labs 或公司向政府推销的方案,传闻政府内部可能有人愿意听取,但目前都只是非公开渠道的消息。

David Sacks

Here's what we know: In the past week, virtually every Trump administration official came out and said some version of what I just said: First and foremost, the AI companies have to take responsibility for their own products, and we will not waive product liability. I think Speaker Johnson said it, the congressional leadership said it, and Scott Bessent said it in his most recent interview.

Everybody said that if your game is to get a waiver of product liability or antitrust liability, if you're trying to form a cartel, if you're trying to collude, forget about it. We're not going to do it. So, I think they completely threw cold water on that whole idea.

And remember what President Trump said—he just tweeted today: We have the DOJ. That's a guardrail. The administration is a guardrail. The administrative state, civil lawsuits, criminal lawsuits—all these things are there as potential liability to make sure that you make the right risk-reward trade-off.

中文

Sacks 说可以确认的是,过去一周几乎所有 Trump 政府官员都强调 AI 公司必须为产品负责,政府不会豁免产品责任;Speaker Johnson、国会领导层和 Scott Bessent 都表达过类似立场。无论企业想免除产品或反垄断责任、组建 cartel,还是进行 collusion,政府都不会同意,已经给这种想法泼了冷水。Trump 当天也发文说 DOJ 和政府本身就是 guardrail,加上行政体系、民事和刑事诉讼,这些潜在责任会迫使公司作出正确的风险收益权衡。

Chamath Palihapitiya

And again, at the end of the day, if those guys release an unsafe product, it's not going to matter what the United Nations agrees on. So, we need them to internalize the responsibility.

中文

Chamath 重申,如果企业发布不安全产品,联合国达成什么协议都无关紧要;关键是让企业把责任真正内化。

Jason Calacanis

Are they? Listen, come on. Be candid with me. You got the inside goods here. Are they trying to lobby for that? Do you think they are lobbying to get this protection? Yes or no? Come on.

中文

Jason 继续逼问 Sacks 是否掌握内幕,要求他坦率回答:这些公司究竟有没有游说政府,希望获得这种保护。

David Sacks

Well, I have heard this. This is not firsthand experience. They have not asked me, “Hey, we want a product liability waiver,” but I have heard from people in Washington that they have been seeking something like that.

中文

Sacks 表示自己确实听到过这种说法,但并非亲身经历;这些公司没有直接向他提出产品责任豁免,不过他从华盛顿人士那里听说,它们一直在寻求类似安排。

Jason Calacanis

It's hard to pin down, right? Yeah. Okay, fair enough.

Friedberg, your thoughts here? As we're going to get into the first story with the token maxing and the prices going down, I'll give you the final word on what America should do in terms of dealing with the corporations that are pretending to be labs, which cannot take ownership of their own Frankenstein creations.

I thought J.D. Vance had a spectacular appearance. He was crisp and looked quite presidential, if I was going to describe it. He threw a lot of fastballs—

中文

Jason 承认此事很难坐实,随后请 Friedberg 在进入 token 性能提升、价格下降的话题前作最后评论:美国该如何对待那些假装自己是 lab、却不愿为自身“Frankenstein”创造物负责的公司。他还称赞 J.D. Vance 的亮相非常出色、表达清楚、颇具总统气质,并说自己向他抛出了许多尖锐问题。

David Sacks

And he knocked them out of the park. By the way, home-run hitters want fastballs. You can't hit a fastball if it's out of the strike zone.

Jason Calacanis

So, I gave him the 3 hardest questions I could think of, and he proceeded to knock all 3 over the fence.

David Sacks

I think JD was excellent.

中文

Sacks 用棒球比喻说 J.D. 把这些 fastballs 全部打成了本垒打,而真正的强打者本来就喜欢好球带内的快球。Jason 说自己提出了能想到的三个最难问题,J.D. 全部漂亮回应;Sacks 也认为他的表现极佳。

Jason Calacanis

Listen, on the Sunday shows, they played the clips of the questions I asked him. Bang, bang, bang. Friedberg, right over the fence.

But he said, basically, if you're creating Frankenstein, here's an idea: Stop. And then he added, if you've already let the cat out of the bag, create anti-Frankenstein. Basically, create the safeguards.

David Sacks

Yeah, it makes total sense.

中文

Jason 说周日新闻节目连续播放了他提问的片段。J.D. 的核心主张很简单:如果你正在制造 Frankenstein,就停下来;如果怪物已经放出笼子,就创造“anti-Frankenstein”,也就是建立 safeguards。Sacks 认为这完全合理。

David Friedberg

I think Zuck gave a good interview on this. They took their time doing this Muse release this week. They said they wanted to get it right. They wanted to make sure that it was safe, that it didn't give people capabilities to do bad things. That's the responsibility that they took as a corporation. Anyone that's outputting a model should take the same responsibility.

Jason Calacanis

Pretty obvious.

David Sacks

This is an organization that understands it, having paid a series of fines from Cambridge Analytica to recently—

中文

Friedberg 认为 Zuck 对此作了很好的解释。Meta 没有仓促发布 Muse,而是花时间确保产品安全、不赋予用户作恶能力,这是公司主动承担的责任;任何发布模型的企业都应如此。Sacks 补充说 Meta 经历 Cambridge Analytica 等事件、支付过一系列罚款,已经理解责任意味着什么。

Chamath Palihapitiya

We have a lot of laws that make it illegal to do a lot of things.

Jason Calacanis

All right, let's move on here. We have laws.

中文

Chamath 指出,现有法律已经把许多行为明确规定为违法。Jason 同意,并准备进入下一个话题。

David Sacks

By the way, can I add one philosophical point to this? I think that implicit in what I'll call the Dario position—the regulated free market that we have—is the fundamental contention that it will lead to a race to the bottom, that competition jeopardizes safety. It's in all of his blog posts, and many other people reflect this idea that competition equals a lack of safety.

That is implicitly a critique of our economic system. It's basically a left-wing critique of our system, and it goes back a long way. I remember back in the days of the Cold War, when we really had this dual between 2 different systems: Do you want the free-market system, or do you want the communist system?

A lot of people made the claim that the capitalist system would do things like jeopardize safety and beauty, that our buildings would always be uglier because the greedy capitalist wouldn't want to spend a dime on beautification or good architecture, things like that. In fact, it turned out that the Soviet system was the one that produced the cold, gray landscapes. Why? Because people want beauty. They want safety.

Therefore, if you have a well-functioning market economy, it gives people what they want. Obviously, the American system won out in that battle. So, I fundamentally disagree with the idea that competition means a lack of safety.

As Zuckerberg and Jensen were saying, there are huge incentives on both the upside and downside to be safe. On the upside, no customer wants a product that is unpredictable and unreliable, that doesn't do what it says. No enterprise wants an agent that's going to leak their data or hack a competitor.

On the downside, as the president made clear, they've got tons of liability: product liability, civil liability, administrative liability, and criminal liability. So, I firmly disagree with this idea that competition is a bad thing. Competition is a good thing that can be harnessed to get the right result.

And just to build on that, Chamath, our friend Nikesh from Palo Alto Networks, a friend of the pod, released Unit 42 in the past week or so. He's building—there's a business opportunity here—to build a product for continuous cyber defense. Also, our friend George Kurtz from CrowdStrike released Falcon, his new product for cyber defense.

Chamath, if these frontier labs and corporations were so concerned about cybersecurity, why didn't they ever release a cybersecurity product? Palo Alto Networks and CrowdStrike are on it, like they will. That's probably more in the second topic we'll talk about, which is that as the models essentially cluster in terms of capability, there's no differentiation, and so they'll be forced to move up the stack. But let's wait on that for 1 second. You have a point here you want to make, and then we'll go to the first.

中文

Sacks 补充一层哲学观点:Dario 所代表的立场隐含着“竞争会导致逐底竞争并危害安全”,这其实是对市场经济的左翼批评。冷战时期,人们也声称资本主义会牺牲安全与美感,因为贪婪企业不愿为建筑美化花钱;现实中却是苏联系统造出了冰冷灰暗的环境,因为人们本来就想要美和安全,运作良好的市场会提供这些东西。他因此反对把竞争等同于不安全。Zuckerberg 和 Jensen 也强调,安全同时有正向和负向激励:客户不想要不可预测、不可靠、会泄露数据或攻击竞争对手的 agent;企业又面临产品、民事、行政和刑事责任。竞争可以被用于产生正确结果。Palo Alto Networks 的 Nikesh 推出 Unit 42,CrowdStrike 的 George Kurtz 推出 Falcon,都在抓住持续网络防御的商业机会。如果 frontier 公司真如此在意 cybersecurity,为何自己从没做过安全产品?随着模型能力趋同、差异消失,它们最终会被迫走向技术栈上层,进入 cyber、法律、客服等具体业务。

Chamath Palihapitiya

I do. The point I wanted to make is more philosophical and sociological. The last time we heard the word “lab” in the social consciousness was during COVID, and there was a lab that was responsible for a leak of a virus that then killed 15 million people all around the world and caused $45 trillion of damage. It's the Wuhan lab.

I think it's important to recognize that there has been zero transparency or culpability around this. Part of why people are comfortable calling themselves a lab is because of that fact. A lot of these young people who work at these places lived through this and saw absolutely no responsibility taken by the lab that caused this leak.

Now we're talking about leaks of different kinds, and we have organizations and corporations that try to fashion themselves as labs as well. But they're not labs. These are corporations. I just want to remind everybody: These are for-profit corporations that have absorbed hundreds of billions of dollars of debt and equity, that have thousands and thousands of shareholders, and that have trillions of dollars of market cap.

If I were them, I would not want to call myself a lab at any cost. And I think if you saw the recent speeches that they gave at the United Nations, they're still using that terminology.

中文

Chamath 从社会和历史角度说,“lab”上一次强烈进入公众意识是在 COVID 时期。他主张武汉实验室泄漏病毒,导致全球 1,500 万人死亡和 45 万亿美元损失,却没有任何透明度或责任追究;许多年轻人亲眼看到 lab 不用负责,因此今天一些机构也愿意这样称呼自己。如今虽是另一种“泄漏”,这些机构仍试图以 lab 自居,但它们其实是吸收了数千亿美元债务和股权资本、拥有数千名股东和数万亿美元估值的营利公司。他认为无论如何都不该再使用 lab 这个名称,可它们最近在联合国演讲中仍沿用这种说法。

Chamath Palihapitiya

Yeah.

David Sacks

They are not labs. These are for-profit corporations that are subject to product liability risk, and they should act accordingly.

Jason Calacanis

Yeah. We've had a conversation here for a year about this. If this stuff is so dangerous, you don't have to release it. My proposal is: Know your customer and give logs.

中文

Sacks 强调它们不是 labs,而是要承担产品责任风险的营利公司,行为也应符合这一身份。Jason 说节目讨论这个问题已有一年:如果技术真的危险,公司完全可以不发布;他的方案是做好 KYC 并提供日志。

Chamath Palihapitiya

Do not compare yourself to the Wuhan lab. It's bad PR, but I do think it's part of their virtue-signaling routine. They just don't want to say that they're companies with a for-profit incentive. They always want to say that they're either a research institution, or they say things like, “We're a public benefit corporation,” which no one really knows what the hell that means.

So, it's this patina of virtue signaling that obscures what's really going on.

Jason Calacanis

It tries to obscure the word “corporation,” but legally you're not allowed to hide it.

We are all running corporations. All-In, albeit very small but mighty, is a corporation. I think we should call it—

中文

Chamath 建议这些公司别把自己与武汉实验室相提并论,这在公关上很糟糕。他认为“lab”或“public benefit corporation”等说法是一层 virtue-signaling 的外衣,用来回避它们受营利动机驱动的公司本质。Jason 说这种措辞只是想淡化 corporation,但法律上无法隐藏;All-In 虽然规模小,却同样是一家公司。

Chamath Palihapitiya

It's the All-In Lab.

Jason Calacanis

This is the All-In Lab, where we discuss different formulas.

David Sacks

No, we're experimenting with ideas. This is a meme workshop.

中文

众人顺势开玩笑,把节目改称“All-In Lab”,说这里研究各种公式、试验不同观点,本质上是一间 meme workshop。

Jason Calacanis

Lab. These ideas are getting so dangerous that we don't want any liability for our opinions. Welcome to the All-In Lab podcast.

Friedberg, is there a mindset in scientists' minds that needs to have a hard stop, and then the corporation kind of takes over? Maybe they could put the labs on the side here and say, “Hey, these are the adults doing the corporation stuff.”

What are your thoughts here if you were going to architect how Anthropic operates in the world? And maybe you could speak to scientists' views of the world versus capitalists and management teams?

David Friedberg

I don't have a good answer for you on that.

中文

Jason 继续玩笑说节目观点越来越危险,所以也想以 lab 身份逃避责任。随后他认真问 Friedberg:科学家的思维是否需要一个明确止点,再由公司管理层接手;如果让他设计 Anthropic 的组织方式,该如何划分科学团队、资本和管理团队的职责。Friedberg 坦言自己没有好答案。

00:20:03

Non-frontier performance and cost: What this means for frontier companies

Jason Calacanis

Okay. Well, you're doing it. You're the answer.

Let me kick off the first topic. What I wanted to do was take a step back and look at the insane flurry of model releases happening. I think the pace of model releases on both the open-source side and the premium side—the Anthropics and Groks of the world—is unfathomable right now. The list is insane.

Just in the last 10 days: on September 9, DeepSeek 4.1 Flash gets released at $0.20 per million output tokens if they're hosting it. The key-value cache from V1 of DeepSeek—remember what a big deal DeepSeek was when it came out—was like 390,000 bytes. Now it's 890. Insane drop, insane efficiency improvements.

On September 20, Qwen, which is the Alibaba model, comes out with version 2.1. It's an open-weights model that outperforms Nano Banana 2, which is Google's big breakthrough, insane image-generation model. This thing is free and open source. You can put it on your desktop computer and run it at home to generate images for free, and it's made by Alibaba.

Xiaomi put out MiMo on September 22, 2 days ago. MiMo Pro performs on par with Claude's Opus 5, which is this insane model that everyone thought was going to change the world and break the internet, and GPT56 Soul across most benchmarks. It's a 309-billion-parameter model. It is entirely open. You can download this model, put it on your server, and run your own instance without paying anyone any money except for the cost of running the server.

This model called Bonsai 2 came out on September 17 from Prism ML. This is actually a fork of Qwen, which is another one of the Alibaba models. It's a 27-billion-parameter model with 98% of the performance of the big Qwen model. It's 5.9 GB in size, and you can run it on a local computer. You can have an NVIDIA chip or a good Mac Studio computer, and you can run this insane model on your desktop computer for free.

Then the big, crazy models—the big closed-source models: Anthropic releases Opus 55 on September 22. OpenAI's Astro comes out with Soul and Luna on September 23. Grok 4.7 comes out on September 21. Meta Muse comes out on September 22. Any one of these stories would have broken the internet a year ago, and they all happened in the last 10 days.

You now have an entire catalog of open-weights models to generate visual information and do VLA, where you can actually instruct the model and it can control a robot. You have models far beyond the most advanced LLM from a year ago that are open weights, that you can install and run on your desktop computer.

We are past the point of Bernie Sanders saying, “Put the superintelligence away. It can never be allowed in the real world.” This stuff is out. The open-source, open-weight models are free. They are on the internet. You can go and download them and run them on your computer at home.

I don't know in what world we think we're going to have a police state that's going to come bang down your door, take your desktop computer from you, and test it to see if you're running an LLM on your local computer. The efficiency wave is here, and the pace at which these models are coming out now—all of this stuff happened in the last 10 days—is just mind-blowing.

We're now in this kind of frontier space where things are accelerating. The performance improvements and the cost decline are making AI so performant and so affordable that it is going to be ubiquitous, and we are all going to benefit from it. This is not just about Anthropic and OpenAI, with the closed-source world making billions of dollars selling enterprises hosted models. There is so much proliferation right now.

I thought it was worth taking a step back to recognize where we are, because in the context of, “We have to stop the superintelligence. We have to shut down the data centers,” you don't even need data centers to do 90% of what you can do with AI. You can download it on your computer for free today and do what was the most advanced technology in human history less than a year ago. It's all here today.

I thought it was worth taking a beat to step back and make sure we all recognize that as we get into this debate about these labs or corporations. I don't know if it even matters anymore. I think open source is here, and I think the pace of improvement is such that this is only going to drive productivity.

中文

Jason 说 Friedberg 本人所做的事就是答案,随后系统梳理近十天密集到难以想象的模型发布。DeepSeek 4.1 Flash 的百万输出 token 只需 0.20 美元,KV cache 从早期约 39 万字节降到 890;Alibaba 的 Qwen 2.1 是开放权重模型,图像生成性能超过 Google 的 Nano Banana 2,可在家用电脑免费运行;Xiaomi 的 MiMo Pro 在多数 benchmark 上接近 Claude Opus 5 和 GPT56 Soul,是可自行下载部署的 309B 参数开放模型;Prism ML 基于 Qwen 的 Bonsai 2 只有 27B 参数、5.9GB,却达到大模型 98% 的表现,可直接在 NVIDIA PC 或 Mac Studio 上运行。与此同时,Anthropic Opus 5.5、OpenAI Astro 的 Soul 与 Luna、Grok 4.7、Meta Muse 也在数日内先后推出。一年前任何一个发布都会轰动互联网,如今却集中在十天内。开放模型已能生成视觉内容、执行 VLA 任务并控制机器人,普通人也能在桌面设备上运行超过一年前最先进 LLM 的模型。Bernie Sanders 所说的“把 superintelligence 锁起来”已经不现实:模型已在互联网广泛流传,不可能用警察上门检查每台个人电脑。效率浪潮和成本下降会让 AI 无处不在,价值也不再只属于 Anthropic、OpenAI 向企业出售 hosted models;即使没有大型 data center,个人电脑也能完成 AI 90% 的常见任务。无论还叫 lab 还是 corporation,open source 已经到来,快速进步只会继续推动生产率。

David Friedberg

Maybe we are seeing the AI wave underway right now—the productivity wave, the productivity boom.

中文

Friedberg 说,也许 AI 带来的 productivity wave 和生产率繁荣正在此刻真正展开。

Jason Calacanis

Yeah. To consumers, they don't care what model they're using. We've spent the last 3 years geeking out about this, and then Grok comes out and Muse comes out from Meta. I've been using both of these products, and it's the first time that a normie—a normal person in the world, not meant to be derogatory in any way—can get value from AI.

If you look at how we all looked at this, running corporations and investing in them, we took a different approach: maybe this is going to retire some positions, maybe this is going to add some positions here or there. But now, with Muse, you can connect to everything instantly and actually get real work done in the world if you're a normal person who wants to get the benefit from AI.

We will be turning a corner, Friedberg, and I think you laid it out perfectly. We're going to turn a corner at the end of this year, where moms, our uncles—people—are going to start using Muse and Grok, which are growing very quickly, to solve real-world problems. They're going to go, “Wait a second. I could never afford a chief of staff. I could never afford a personal assistant, an executive assistant. Now I get a free executive assistant.”

It's going to blow people's minds, Chamath, in the next couple of months when they start using these products, and the bottom half of America in this K-shaped recovery experiences some benefits. Your thoughts on what's happening here with these models? Have you started playing with them? Because you were originally a technologist. Have you loaded these models on your computer? I'm playing with them on my MacBook Pro, and it's awesome.

中文

Jason 认为消费者根本不关心底层用哪个模型。业内人钻研模型三年后,Grok 和 Meta Muse 首次让普通人真正获得 AI 的直接价值。企业过去主要讨论岗位替代或新增,但 Muse 能快速连接各种服务,让普通用户完成现实工作。到今年年底,母亲、叔叔等普通人会开始用 Muse 和 Grok 解决日常问题,第一次免费获得过去负担不起的 chief of staff 或 executive assistant。这会让处在 K 型复苏下半边的美国人也感受到好处。他请原本就是技术人员的 Chamath 分享体验,并说自己已经在 MacBook Pro 上运行这些模型,感觉很棒。

Chamath Palihapitiya

Let me give you the answer by explaining something. I think what we're seeing is that these models are converging and clustering, which is to say that they're now within the margin of error. There are so many of these models that are roughly the same at different price points. So where is the edge?

There's still an edge, and the edge is in the harness that you use to wrap the model. If you think about it, you have a model that's like a brain, but you need to embody that brain with arms and legs and hands and eyes to do work. That's how you make it agentic; that's what that phrase means. There are all kinds of different harnesses that the industry has invented to make these models more agentic.

At 8090, we have a labs function, and we've been ripping and teasing apart all the different models with all the different harnesses just to see how they perform. They vary wildly in terms of cost and quality. To build on Friedberg's point, you have the models that are converging, but the harnesses are wildly different, so their performance is all over the map. Now companies and people have to navigate what they're willing to pay for.

I sent this tweet to Nick. If you can just put it up here, I don't know if this is instructive or accurate, but what this shows—and this is the case for Anthropic, but it's probably the case for a lot of the closed models—is that you're starting to see this massive revenue concentration, where a few folks consume all of the highest and most expensive tokens.

I think if you take what Friedberg just showed to its logical conclusion, those folks at the top of this table are going to be under a lot of internal pressure, whether it's from their finance teams, their CFO, or shareholders, to explain why, as this clustering happens, they are not moving down to cheaper and cheaper models.

You may choose to go down to cheaper and cheaper Anthropic models, so Anthropic keeps the revenue, but there's also a risk that you may do what Friedberg just said and go to an open-source model and host it yourself. We're in a very complicated part of the cycle.

The first version of the AI trade was relatively simple: you're just selling tokens, wrapping the tokens, and passing them through. There was enough disparity that there was value. I think that's going away. It will force OpenAI and Anthropic to go up the stack. There is no choice. You can't sit there and serve a token that has diminishing value, because then all the subsequent value is getting absorbed and made by people wrapping your intelligence token. You will have to do that work.

Jason, that's why they will have to go and do cyber. They'll have to go and do law. They'll have to go and do customer support—all these things that we weren't sure whether they were going to compete in. These trends may force them to do that.

中文

Chamath 说模型正在收敛、聚集,许多模型的能力差异已经落入误差范围,价格却不同。真正的 edge 转向包裹模型的 harness:模型像大脑,但需要手脚和眼睛才能做事,harness 使其具有 agentic 能力。8090 的 labs 团队拆解测试各种模型与 harness 组合,发现成本和质量差异巨大;模型本身趋同,harness 的性能却分布很散,企业必须判断愿意为何种组合付费。闭源模型的收入也越来越集中在少数消耗最昂贵 token 的大客户身上。随着便宜模型逼近,CFO、财务团队和股东会要求这些客户解释为何不降级;他们既可能换到 Anthropic 更便宜的型号,也可能转用 open-source 并自行托管。最初 AI 生意只是出售 token、简单包装后转售,能力差异足以创造价值;这种差异正在消失,迫使 OpenAI 和 Anthropic 向上游应用层发展。token 本身价值递减,后续价值都被包装智能的人拿走,因此它们必须亲自进入 cyber、法律、客服等业务。

Jason Calacanis

Yeah. I think then that sets up a very interesting setup for their IPO. Just to back all that up, Sacks—

中文

Jason 认为这些变化会给两家公司的 IPO 带来一个非常有意思的局面,并把话题交给 Sacks。

00:29:22

Anthropic and OpenAI postpone IPOs: liquidity risk and open source pressure

David Sacks

The frontier lab corporations, Anthropic and OpenAI, both released models this week at 50% lower token prices, and their IPOs are looking like they're both going to get delayed.

Anthropic is targeting a $2 trillion valuation, and OpenAI is targeting $1.2 trillion. Sam already said OpenAI plans on doing an IPO in 2027, in part because of safety concerns. Anthropic, which was supposed to file and go out in October—the report from The Wall Street Journal is that the IPO will happen in November or may be delayed even more.

中文

Sacks 说 Anthropic 与 OpenAI 本周都把模型 token 价格降低了 50%,但两家的 IPO 看来都会推迟。Anthropic 目标估值 2 万亿美元,OpenAI 目标 1.2 万亿美元;Sam 已表示 OpenAI 因安全顾虑计划到 2027 年再上市。Anthropic 原本要在 10 月申报上市,但《华尔街日报》称可能移到 11 月,甚至进一步延期。

TIMESTAMP_UNVERIFIEDJason Calacanis

Anthropic peaked at 96% earlier this month that it would go public this year, but now it’s fallen to 76%. Is this like a sell signal here, Sacks? The leading model companies need to go public to get capital to do their buildout, and now they’re delaying their own IPOs.

Please explain how any of this makes sense. If you were a major investor in one of these companies or on the board of one of them, what would you be doing or instructing these founders to do to get these companies to go public and get the capital they need to continue the AI buildout?

中文

Jason 引用预测市场数据说,Anthropic 年内上市的概率本月早些时候一度达到 96%,如今跌到 76%,问这是否是 sell signal。领先模型公司需要上市融资建设基础设施,却又主动延迟 IPO;他请 Sacks 解释其中逻辑,并设想如果自己是主要投资者或董事,会如何推动公司上市、取得继续建设 AI 所需资本。

David Sacks

I think that we know from our friends that the investors in Anthropic are pulling their hair out about what’s happening right now. Forget about the fake whistleblowers who were there for a few weeks and then left. You have current leadership in the company saying that there’s a greater than 10% chance of causing human extinction, and their own product is unsolved in this area. Think about the risk factors that’s creating. How do you IPO with your own management of the company saying that?

Then you’ve got what I don’t know how to call except corporate schizophrenia. You’ve got Dario putting out this essay saying we need to pause the frontier days before they launch Claude 5.5 and set a new frontier. He must know when he’s writing this essay that they’re about to release a product that will extend the frontier. At a minimum, it’s hypocritical, but maybe it’s even worse than that.

Then you have them publishing an essay about the biorisk associated with AI and how that needs to be stopped. Meanwhile, they announce a new biolab in San Francisco, a new wet lab.

中文

Sacks 说从共同朋友那里得知,Anthropic 投资者已经为当前局面急得抓头。不是只待几周就离职的所谓 whistleblowers,而是现任管理层公开声称公司产品有超过 10% 概率导致人类灭绝,而且问题尚未解决,这会在 IPO 文件中造成巨大风险。更像“企业精神分裂”的是,Dario 刚发表文章主张暂停 frontier,数天后公司却发布 Claude 5.5、再次推进 frontier;他写文章时不可能不知道产品即将发布,至少是虚伪,可能还更严重。公司一边发表文章警告 AI 生物风险必须阻止,一边又宣布在旧金山建立新的 wet lab。

Jason Calacanis

They started a lab after telling us that there’s a 10% chance of us all dying. Sacks, let’s just pause here for a second. Is this a dereliction of duty as the chief executive officer of Anthropic to sabotage your own IPO? You’re supposed to be acting on behalf of your shareholders.

This, to me, seems like if we were the board—if the 4 of us were somehow magically the board of Anthropic—we would replace the CEO. We would put Dario in the lab, and we’d find a CEO who knows how to run the company and not sabotage it. He’s literally sabotaging his own company.

中文

Jason 说 Anthropic 刚告诉公众公司有 10% 概率让所有人死亡,却转身开了一间实验室。他问这是否构成 CEO 失职并蓄意破坏 IPO,因为 CEO 理应代表股东利益。如果四位主持人组成董事会,他认为应更换 CEO,让 Dario 专心留在实验室,再找一位懂得经营且不会破坏公司的负责人。

David Sacks

I think there’s an element of that, and I think investors are pretty nervous about giving the founders, or Dario specifically, super-voting shares. There’s a story in The Information about that, that there’s an active debate right now about whether to give them super-voting shares.

Jason Calacanis

Explain what those are, please, and why, in this context, this is critically important. Our audience may or may not know what those are.

中文

Sacks 认为确有 CEO 破坏 IPO 的成分,因此投资者对于给创始人、尤其 Dario super-voting shares 很紧张。《The Information》报道称,是否授予这种股份正在激烈讨论。Jason 请他解释其含义以及为何在此情境下格外重要。

David Sacks

Supposedly, the founders of Anthropic only have about 2% ownership each of the company, which in the grand scheme of things is a relatively low number compared with what other founders typically have at the time of an IPO. It’ll still be an enormous amount of money—tens of billions of dollars—but that is the case.

Super-voting shares basically separate the economic shares from the voting shares in the company and give certain people the right to control the company even if they don’t have the economic ownership that would usually be necessary. It’s a pretty common thing. Larry Page and Sergey Brin, I think, may have been the first prominent founders to get super-voting shares in Google, and Mark Zuckerberg did as well.

It can be a stabilizing thing for the company because it means that, as long as the founders are there overseeing things, they’re not going to be subject to takeover attempts or things like that. But on the other hand, it requires a tremendous degree of trust in those founders because they effectively can’t be removed no matter what they do. You just have to wonder if, in this case, that’s earned and warranted.

I have to say that even for someone like me who isn’t necessarily advocating for a lot more regulation, I kind of get nervous about the idea of Anthropic opening a wet lab in San Francisco.

中文

Sacks 说据称 Anthropic 每位创始人只持有约 2%,比一般公司 IPO 时的创始人比例低,虽然价值仍达数百亿美元。Super-voting shares 把经济权益与投票权分离,即使某人没有通常所需的经济持股,也能控制公司;Larry Page、Sergey Brin 和 Mark Zuckerberg 都采用过。这可以防止创始人在任时遭敌意收购,稳定公司,但也要求投资者高度信任创始人,因为无论他们做什么都几乎无法被罢免。Anthropic 是否已经赢得这种信任值得怀疑;即便 Sacks 不主张大幅增加监管,他也对 Anthropic 在旧金山开 wet lab 感到不安。

Jason Calacanis

Great timing.

David Sacks

I was thinking about moving back, and I don’t know if I want to be—I mean, can you just put it a little further away? I think we’ve all seen this movie before.

Jason Calacanis

Yeah. Offshore, maybe. I don’t know. Put it on an oil rig or something.

中文

Jason 讽刺说时机选得真好。Sacks 原本考虑搬回旧金山,如今却不想住得离实验室太近,因为大家仿佛已经看过这部电影;Jason 开玩笑建议把实验室放到离岸油井平台上。

Chamath Palihapitiya

What I would say is that if I were on the board, I would keep Dario as CEO. The reason is that he’s clearly demonstrated that he can build a unique culture and position against the otherwise most formidable corporate competitor, which is OpenAI. He’s done that, and he’s come from behind. I don’t think you should undervalue how hard that is and what that takes.

He’s built essentially the greatest business ramp of all time. I think the thing that I would probably do if I were on the board is fix what Sacks just said, which is that there’s now a bunch of incremental liquidity risk to the company. If you take the 20-year view on Anthropic, that corporation needs hundreds of billions of dollars to fulfill its ambitions. I would solve for getting that as risklessly as possible.

I think there are only 2 things that you can do. The first is you have to throw everything, including the kitchen sink, into disclosures. The problem is that that will make what is an otherwise dense and impenetrable S-1 even more dense and impenetrable. You can superficially cover your regulatory risk, but the way that it actually gets translated in the market is that you’re going to have to water down the expectations of the IPO sellers and create a much larger margin of safety for the IPO buyer.

That’s effectively how you find a market-clearing price for this, Jason, which is to essentially say—and bear with me, I’m just giving out rough numbers—even if you think that they’re on a $100 billion run rate, what otherwise, in a very clean-sheet IPO, maybe would have been a $2 trillion market cap, now you’re at $1 trillion or less.

The reason is that the hedge funds and the pension systems and the long-only mutual fund complexes, which have a fiduciary responsibility to their sources of capital, will justify all the risks by essentially asking for a lower and lower price. I think that’s what you’re going to see. I think you’re going to see a much more moderate and reasonable IPO valuation here, and it’s probably going to clear at a much lower price than anybody thinks.

I do think that what Sacks says is the reason why. But I think it’s good for Anthropic because it clears all this noise. It forces them to just be a corporation and then run the business, and I think that they’ll do great.

Look, I’ll be honest with you: I’ve tried to recruit against Anthropic. I can’t. It’s impossible. The compensation that they give is incredible. The business ramp is so compelling. When you’re in a head-to-head with these guys, I have not won a single bake-off for folks. I wish I could say that I did, but I have not, and it’s hard for a startup.

They are a magnet for talent. OpenAI is a magnet for talent. But these other risks are going to weigh on the IPO, and the only way to flush them is to just bring the price way down.

中文

Chamath 表示如果自己在董事会,仍会保留 Dario 做 CEO,因为他已经证明能建立独特文化,从后发位置挑战最强对手 OpenAI,这种难度不应低估;Anthropic 也创造了近乎史上最快的业务增长。董事会真正该解决的是新增的流动性风险:从二十年视角看,公司需要数千亿美元实现雄心,应尽可能低风险地筹资。第一步是在 S-1 中披露一切,但这会让本来就晦涩的文件更难读;市场最终会通过降低卖方估值预期、给 IPO 买方更大安全边际来吸收风险。即使年化收入达到 1,000 亿美元,原本干净 IPO 可能值 2 万亿美元,现在也可能只有 1 万亿或更低,因为 hedge funds、养老金和 long-only 基金有受托责任,会用更低价格补偿风险。IPO 很可能以远低于预期的、更合理估值成交,但这反而能清除噪音,迫使 Anthropic 作为普通公司经营。Chamath 还坦言自己与 Anthropic 抢人才从未赢过:它给出的薪酬极高、业务增长极有吸引力,是与 OpenAI 一样的人才磁铁;只是这些风险会压低 IPO 定价。

Jason Calacanis

Yeah. And Friedberg, when we look at the risk factors in an S-1, those are perfunctory. Those are disclaimers. Typically, you get the SpaceX one: What if Starship doesn’t work? What if there’s competition? It’s kind of checkboxes.

In Anthropic’s, I think we’re going to be looking at something totally different, which is: We and our employees are saying this is going to kill humanity. We have massive regulation. We’re asking for regulation. And, by the way, we’re doing biology work and launching a lab.

So, do you agree with Chamath here that the S-1 is going to have actual risk factors and disclaimers that are material against the IPO, Friedberg?

中文

Jason 问 Friedberg,普通 S-1 的风险因素常像例行免责声明,例如 Starship 失败或竞争出现;Anthropic 却会写入真正重大的问题:员工声称产品可能毁灭人类,公司面临并主动要求大规模监管,同时还在开展生物学研究、开设实验室。他问这些风险是否会实质性打击 IPO。

David Friedberg

I think this customer-concentration point ties to the earlier comments I made about the proliferation of incredibly performant open-weight and open-source models. The reason is that Anthropic puts out the best models for life sciences today. I run a life sciences R&D organization. We use their models. They’re incredible. They’re better than other models, and so we want to use them.

When it comes to writing code, writing software to do internal workflows and run operations, we can use other products to write that code for us. And we do. I think that’s likely the way the market is going to develop, and I think we’re starting to see that proof come out in the market. You’re seeing it in this customer-concentration point.

Extremely high-value technical engineering, math, and life sciences—those really hard technical problems—you want to have these top-tier, top-shelf models, and you’re going to pay a huge premium for them. You’re totally going to make money doing it because the value is extraordinary.

This has always been my case about AI: AI is not so much about the value of replacing old stuff. 99% of the value of AI is about enabling new stuff that’s never been possible in human history. I think that’s where Anthropic and OpenAI are going to make their money.

Separately, I think OpenAI is going to make a lot of money in consumer, and Anthropic maybe to some extent as well. But in the enterprise setting, I think the money comes from creating new frontiers, discovering new enzymes, which Anthropic announced this week that can cure human disease, and developing new technology and new engineering systems—making things that have never been possible to make before.

I think that’s the premium value, and it’s the premium price you’ll pay for those closed models and that premium model. But that’s a different business case than taking over all of enterprise.

Separately, I think most enterprise applications are going to be run using these open-weight models, and code is going to be written with cheaper models and so on. I don’t know why you would go to a higher-end model to write code when you can do it for free, and everyone in the organization can write code basically for free.

And so I think Anthropic's bigger issue is this customer-concentration question: Is it really a premium product that they're selling in the market, and is that where they take the market? That would be where I think the market is headed right now, and it would be the biggest risk factor. This whole thing about, “Oh, it's going to end the world” and whatnot—it's like, dude, just make sure your product doesn't end the world and you'll be fine. That would be a good first step here, like Mark is doing at Meta.

中文

Friedberg 认为关键风险与客户集中度及高性能 open-weight/open-source 模型扩散有关。Anthropic 在生命科学上拥有最好的模型,他自己的生命科学研发组织就在使用,因为其价值远胜其他模型;但写代码、内部流程和运营软件完全可以用便宜产品。市场会分层:工程、数学、生命科学等极难问题值得为顶级模型支付高额溢价,因为 AI 最大的价值不是替代旧工作,而是实现人类历史上从未可能的新事物,例如发现能治疗疾病的新酶、开发全新技术和工程系统。OpenAI 也会从消费市场赚钱。但多数企业应用和代码会采用 open-weight 及便宜模型,没必要为免费就能完成的编码支付顶级价格。因此 Anthropic 的核心问题是,它卖的是否真是覆盖小众高价值需求的 premium product,而不是整个企业市场。至于“终结世界”的风险,只要像 Meta 那样确保产品不会毁灭世界即可,这是最基本的第一步。

Jason Calacanis

I mean, it's an incredible company. The execution has been extraordinary. The ramp of revenue, Sacks, has been extraordinary. But when you start to look at the impact of open source, we had a couple of viral charts come out. Seventy to 80% of the token usage are those dark tokens I mentioned 6 months ago here on this pod that are not tracked, but some people can track them on routers. Those dark open-source tokens are now the majority of tokens.

David Friedberg

Can I just give you a stat on that, JCal? What you just said is really important, but there's a stat that I think, in the last 12 weeks alone—

Chamath Palihapitiya

Token use has flipped from 80/20 closed versus open—

中文

Jason 说 Anthropic 的执行和收入增长都很惊人,但 open source 影响迅速扩大:他半年前提到、无法通过普通统计追踪却能从路由器观察到的“dark tokens”,已占 token 使用量的 70% 到 80%。Friedberg 正要补充一项最近十二周的数据,Chamath 先说 token 使用结构已经从闭源对开源 80/20 反转。

Jason Calacanis

—to 80/20 open versus closed.

David Friedberg

In 12 weeks, I don't think we've ever seen a tidal wave of change in the history of all technology markets. We've never seen anything like this. And that is the biggest risk factor for Anthropic: They were first out of the gate to get the enterprise on AI, to build tools and whatnot. But as this market shifts to open source and open weights, boom, here it is right here. Look at this.

Jason Calacanis

This is the Vercel chart that went viral this week. So this is 12 weeks. Oh, my God—

中文

Jason 把结论补完整:现在是 open 对 closed 80/20。Friedberg 说技术市场史上从未见过十二周内如此巨大的浪潮,这正是 Anthropic 最大风险:它最早推动企业采用 AI、构建工具,但市场现在突然转向 open source 和 open weights。Jason 展示本周疯传的 Vercel 图表,对变化速度感到震惊。

David Friedberg

Crazy. If you look at this chart, this, I think, is what blows the lid off the door on what needs to go into these S-1s. That's why I walked through all those openweight releases at the start of the show, or this segment: It's not just that they're there; it's that they're proliferating now. There are so many more of them coming out, and the pace of improvement is extraordinary. They're now in VLA for robotics and in image generation for image and video. So the openweight, open-source models are now being used for all of the broader AI applications. The premium stuff, I will say, is still the best for narrow use cases.

Chamath Palihapitiya

For engineering, for highly technical, highly complicated tasks and workflows and problems—

中文

Friedberg 说这张图彻底改变了 S-1 必须披露的内容。开放模型不只是已经存在,而是在快速扩散、性能飞跃,并进入机器人 VLA、图像和视频生成等更广泛应用;不过在少数窄而高端的场景中,premium 模型仍然最好。Chamath 接着指出,这主要包括工程及高度技术、复杂的任务和工作流。

David Friedberg

—solving Navier–Stokes, solving mathematical problems, solving biology problems—that's where these models absolutely perform, and people will pay a premium of, I would say, close to infinity dollars for that premium application set. So it doesn't mean that their market is destroyed. Yeah—

Chamath Palihapitiya

—it means that we're seeing a bifurcation in the market, where the majority of use cases of AI go toward these open-source, open-weight models.

Jason Calacanis

The question is, and premium models are still going to proliferate. Yeah.

Chamath Palihapitiya

The question then is, in the distribution of tokens in these frontier corporations, what percentage are those tasks versus what percentage are fungible tasks for open source? If the answer is more than 60 or 70%, you have to discount that revenue. If the answer is only 10%, and 90% of all of the revenue is being generated on absolute frontier use cases, they're going to be fine and they're going to be off to the races.

中文

Friedberg 举例说,解决 Navier–Stokes 方程、数学和生物学问题时,顶级模型表现突出,客户几乎愿意支付无限高的溢价,所以市场并未被摧毁。Chamath 认为市场正在分叉:大多数 AI 用例流向 open-source/open-weight 模型;关键是 frontier 公司的 token 收入中,真正无法替代的任务占多少。如果 60% 到 70% 以上只是可由开源替代的通用任务,收入就必须大幅折价;如果只有 10% 可替代、90% 都来自绝对 frontier 用例,公司就会继续高速增长。

Jason Calacanis

Yeah.

Chamath Palihapitiya

But otherwise, it's a thing where you're fighting just people's misunderstanding or lack of education, right? Because as they see their bills—

Jason Calacanis

I'll hand it to Sacks here. Yeah, go finish your thought, and then I'm going to hand it to Sacks.

Chamath Palihapitiya

No, just move the workloads where they belong and save the money.

Jason Calacanis

Yeah. And so, Sacks, I made a chart here before the show, but here's your sweet spot for the last 100 days of models, which, Friedberg, you did a good job of teeing up. What you'll see is, yes, the Clouds and the Astros up in that right-hand corner cost a lot and deliver a lot. But then you start going down and you start to see Muse, GLM, and Kimi, and on the left you start seeing GLM from Z.ai and MiMo, and you're starting to see the Chinese—

中文

Chamath 说否则公司只是利用客户不了解替代方案;账单越来越高时,正确做法是把工作负载放到适合的位置并节省成本。Jason 准备让 Sacks 回应,并展示过去 100 天模型的价格性能图:Claude 和 Astro 位于高价格高性能区域,Muse、GLM、Kimi,以及 Z.ai 的 GLM、MiMo 等中国模型则不断从低成本侧逼近。

David Friedberg

This is all hosted, right, JCal? I mean, it's important to note that what you're showing here is the hosted price, but if you run it yourself, the cost on some of these is less than $0.10 for 1 million tokens.

中文

Friedberg 提醒图中显示的是 hosted price;如果自行部署,部分模型每百万 token 的成本甚至不到 0.10 美元。

Jason Calacanis

Yeah. So you'll pick up the compute, you'll pick up the bandwidth, all that other stuff. But, Sacks, the issue here, to Chamath's point, is the vertical language models—the small language models—are going to do 80 or 90% of the tasks that many corporations need. And then we get to AI sovereignty. Do you want your superintelligence? Shout-out, President Trump, from AI Czar, DJT. We need people to use those models so they have sovereignty, so you're not giving your data to the frontier models and they don't get that tip-of-the-spear superintelligence edge, which is why people are disengaging. So your thoughts on maybe this is going to start to impact the velocity of Claude and OpenAI tokens. What does your business sense tell you, David Sacks?

中文

Jason 同意自建仍要承担 compute、带宽等费用,但 vertical/small language models 已能完成企业 80% 到 90% 的任务,这也关系到 AI sovereignty:组织希望掌握自己的模型,不把数据交给 frontier 公司,也不让对方获得最尖端智能优势。客户因此减少依赖 Claude 和 OpenAI,可能影响其 token 增长速度;他请 Sacks 从商业角度判断。

David Sacks

Well, look, wearing my hat as an investor, I'm more optimistic about the frontier intelligence business than I think you guys are. I think that Anthropic and OpenAI right now are a stable duopoly for frontier intelligence because they have a pretty significant lead over all these other companies and they are able to charge a premium for that.

I fully understand that the majority of tokens will go to open models or commodity intelligence. However, there is a—I don't know—meaningful percentage of the market, whether it's 10%, 20%, 30%, whatever, that will pay this huge premium for true frontier intelligence. There are a lot of customers that either need the best or they just want to know they have the best. They don't want this DIY approach, or they could be in a very competitive market. Let's say you're a hedge fund. You can't take the risk that your competitor has a better model than you do. So there are a lot of circumstances where I think they will continue to monetize the frontier at a premium, and this is why you're seeing their revenue keep growing even though they're losing token market share.

Furthermore, you've got to remember that over the next year or so, something like 60% of the worldwide compute that's being added is being added for these 2 companies. To the extent that compute gets scarce and we're kind of in a compute crunch, just the fact that they've made these huge investments, they're building out so much capacity, and they have those economies of scale—and remember, they're bringing down their own prices very quickly as well—I think that gives them a pretty big advantage.

But look, these 2 companies are on a hamster wheel. The moment where they stop being frontier, they go to zero, right? And we know the frontier is maybe only 6 to 12 months ahead of the commodity portion of the market, depending on capability. So, again, if they slip, if they fall off that hamster wheel for 6 months, then they're in deep trouble as a company. And that, I think, is a central risk factor that's going to have to be priced in.

This is where I think that, frankly, their government-affairs efforts are miscalculating badly. I can see why they're going for regulatory capture, right? Because being on a hamster wheel gets really tiring. They probably think, “Let's try and bake in our moats. Let's try and slow everyone else down as well.” But I think they've miscalculated, because if they actually get all the regulatory controls they want, if they create this new federal department of AI, it's going to slow them down enough that they will no longer be frontier. Everyone else will catch up to them, especially because a lot of these open models are being generated by Chinese companies who are not subject to our jurisdiction. And the Chinese have made abundantly clear they are not slowing down.

So think about it: They are lobbying for things that could slow them down and knock them off the frontier, in which case their business goes to zero. It's hard to understand.

中文

Sacks 以投资人身份比其他人更看好 frontier intelligence。他认为 Anthropic 与 OpenAI 目前形成稳定双寡头,领先其他公司并能收取溢价。大多数 token 会流向 open models 或 commodity intelligence,但仍有 10%、20% 或 30% 的市场愿为真正的 frontier 支付极高价格:有些客户必须用最好的,有些只想确保拥有最好模型,竞争激烈的 hedge fund 更不能冒险让对手拥有更强能力。因此即使 token 份额下降,两家公司收入仍在增长。未来一年全球新增 compute 约 60% 会供给这两家公司,在 compute 紧缺时,大规模投资、产能和规模经济会形成优势,它们自身也在快速降价。但这是一台 hamster wheel:只要不再处于 frontier,商业价值就可能归零,而 frontier 仅领先 commodity 市场约 6 到 12 个月,落后半年就会陷入大麻烦。这也是必须计入估值的核心风险。它们试图通过 regulatory capture 建立 moat、拖慢别人,却可能误判:若真的建立联邦 AI 部门和重监管,自己也会被拖慢,让不受美国管辖且明确不会减速的中国 open models 追上。游说会把自己挤下 frontier,让业务归零。

Jason Calacanis

They're lapping the competitors in this race, and they're asking, “Hey, can you pull us over and inspect the engine?” Chamath, that makes no logical sense. On top of that, Chamath, you have very significant competition, not just from the Chinese, but from Jensen at NVIDIA. You also have Microsoft, Satya, Google, and Meta at Zuckerberg's house. They're all embracing open-source models, and they all have hosting now.

中文

Jason 说这像公司正在赛道上套圈对手,却主动请警察拦车检查引擎,毫无逻辑。竞争也不只来自中国,还有 NVIDIA 的 Jensen、Microsoft 的 Satya、Google 和 Meta;这些巨头都拥抱 open-source 模型,也都提供 hosting。

Chamath Palihapitiya

Yeah. Can I just go back to what Sacks said, which is a really important and nuanced point that I just want to double-click on? He said, “Imagine you're a hedge fund and you need the absolute latest and greatest because you are worried that one of your competitors has it.” This is a really interesting question because it's about game theory and your P&L.

So now you're in this game of chicken with your competitors. You need to use the best because you're afraid that they could use the best and outcompete you. But what is the problem right now? What we know is that you can consume an inordinate amount of tokens, right? We jokingly call it token-maxing. That cost is completely not levered or attached to your revenue. It's just not.

And so, all of a sudden, you have this very weird dynamic where you're like, “Okay, well, am I supposed to use this latest and greatest thing that's 10 to 20 to 30 times more expensive than a generic thing?” That thing isn't tied to my revenues; it's not like I can pass that through, right? So, if a hedge fund only makes X number of dollars per month in profits, there are a lot of scenarios where they can become break-even to unprofitable.

Now, take a different example. Let's just say that you sell a physical good at a fixed price. Yet again, I think you have this example where you could use the latest and greatest, and if you're not able to pass those costs through and inflate your price to absorb the cost of that service, you're in a very tough spot.

中文

Chamath 回到 Sacks 所举的 hedge fund 案例:基金因担心竞争对手使用最强模型而不得不用最新最好产品,这是一场关乎 P&L 的 game theory 困局。但所谓 token-maxing 可以消耗巨量 token,成本并不与收入挂钩。公司是否应使用比通用方案贵十到三十倍的模型?如果无法把成本转嫁给客户,利润就会被吞掉,甚至从盈亏平衡变成亏损。销售固定价格实体商品的公司也一样,不能涨价吸收 AI 成本就会非常困难。

Jason Calacanis

So, I'm not sure, Sacks, I agree with this because I don't see the pricing power of these companies to both pay for a ton of these super-expensive tokens and also pass that through to their customers. If you can't, they're just absorbing it, and you're going to see it in lower margins.

To build on that, Sacks, I'm going to drop it back to you. If you take Jane Street, a very famous trading firm, they've publicly announced $19 billion in cloud-capacity contracts. CoreWeave has $6 billion in cloud commitments. They also invested in that company, and then $13 billion with Crusoe.

They're building their own infrastructure, and they're embracing open source. So that speaks to Chamath, what you're saying. Are they hedging their bets? They're going to spend tens of billions of dollars on their own compute, and they're going to use the frontier models, it seems. When you do the game theory, you're saying, “Hey, let's embrace our own infrastructure, Sacks.”

中文

Jason 因此不同意企业能长期支付昂贵 token 并把成本转嫁给客户,否则只能接受利润率下降。他以 Jane Street 为例:该交易公司公开签了 190 亿美元 cloud capacity 合同,另有 CoreWeave 60 亿美元承诺并持股,以及与 Crusoe 的 130 亿美元协议。它正在建设自己的基础设施、拥抱 open source,同时也会使用 frontier models,相当于用数百亿美元自有 compute 对冲风险。

David Sacks

Well, look, I think when your use cases become more mature and you can get by with cheaper commodity intelligence, then obviously you'll try and build that out again, if you have the sophistication level to do it. I just think it's easy to underestimate how convenient it is to use the frontier. Again, these companies are very rapidly bringing down their prices, too.

We've talked about this. At the end of the day, there's no question that open source is a huge risk factor to Anthropic's S-1, and it has to be right up there with the risk that they're going to end humanity or something like that. But I come back to the fact that I think the fundamental problem with this company is that it's schizophrenic. I think they need a psychiatrist, not a banker.

They keep doing things that are hypocritical and oxymoronic. On the one hand, they're saying “pace of frontier” as they release a new frontier model. They say that bio-risk can end humanity as they open a wet lab in San Francisco. They say their business depends on staying ahead of the commodity models, and they are advocating for a federal Department of AI that will definitely slow them down, perhaps to the point where they get commoditized.

So you have a fundamental breakdown happening in the leadership of this company, where they are advocating for things that are likely not in their interest. Now, a lot of people say it's just regulatory capture, and that is true. But I think the regulatory capture is the government affairs people trying to rationalize the schizophrenia and make it work to their advantage. I'm not sure that it fully computes, so to speak.

中文

Sacks 说用例成熟后,只要组织具备能力,自然会用更便宜的 commodity intelligence 自建,但人们也低估了直接使用 frontier 的便利,而且两家公司正在快速降价。Open source 无疑是 Anthropic S-1 的重大风险,重要程度可以与“毁灭人类”并列;但公司更根本的问题是内部“精神分裂”,需要的像是 psychiatrist 而非 banker。它一边主张放慢 frontier,一边发布新的 frontier 模型;一边警告生物风险毁灭人类,一边在旧金山开 wet lab;一边依赖领先 commodity models 生存,一边主张设立必然拖慢自己的联邦 AI 部门。领导层正在推动不符合自身利益的政策。所谓 regulatory capture 可能只是政府事务团队试图合理化这种矛盾,但逻辑未必成立。

00:53:11

Political reactions to "Pacing the Frontier": Bernie's AI ban, Trump, Bessent, Obama

Jason Calacanis

Yeah. Let me ask you guys a question. What do you think would be the method by which a ban on superintelligence would work? Bernie Sanders proposed this bill to ban superintelligence, and the Democrats take the House, they take the Senate, and then maybe in 2028 take the White House. You end up in a world where this sort of thing is so weirdly political, which it shouldn't be.

I don't understand how we ended up with a political-party divide on progress. It's—

中文

Jason 问所谓禁止 superintelligence 究竟如何执行。假设 Bernie Sanders 的法案通过,民主党控制众议院、参议院并在 2028 年赢得白宫,AI 进步竟然变成政党分歧,令他难以理解。

David Sacks

They ask for it. That's the reason they asked for it.

中文

Sacks 说之所以会出现这种政治分歧,正是因为相关公司主动要求政府介入。

Jason Calacanis

No, there's—it's so awful and weird that you're anti-progress because of your political party. The whole thing isn't objective. It's a bunch of weirdly distorted-worldview thinking to try and create an opponent out of the individuals that you don't like. It's very weird.

Anyway, my point is, even among the Republicans, you're hearing murmurs about, “Well, maybe we should ban data centers, ban AI.” So, Sacks, let me just ask you: What is the pragmatic path with all of the open-source, open-weight models being out there? Is there even a pragmatic path to do what everyone's stating or talking about—or what Bernie is talking about—which is to ban superintelligence, to stop AI, to turn it off?

Is there even a way to do this? What would happen if this law passed tomorrow? What do you think would happen if Bernie's bill passed tomorrow?

中文

Jason 认为因党派立场反对进步既糟糕又怪异,这不是客观判断,而是扭曲世界观、把不喜欢的人塑造成敌人。如今甚至一些共和党人也开始谈禁止 data center 和 AI。他问 Sacks,在 open-source/open-weight 模型已经广泛流传的现实下,禁止 superintelligence、关闭 AI 是否还有任何可行路径;如果 Bernie 的法案明天通过,究竟会发生什么。

David Sacks

If Bernie's bill passed tomorrow, everything would stop, because the way he defines artificial superintelligence in his bill, you could argue we've already hit those thresholds. I mean, the way—it's basically just saying that models have—

Jason Calacanis

Yes.

David Sacks

—reached a certain capability level. I think it's arguable whether we've already reached it or not, so it's a very loose definition. On top of that, he's got 20-year prison sentences for developers who violate the law. No one's going to want to take the chance.

Jason Calacanis

So what happens?

David Sacks

Think about that chilling effect.

中文

Sacks 说一旦法案通过,所有开发都会停止,因为法案对 artificial superintelligence 的定义只是达到某种能力阈值,而现有模型是否已经越过阈值都存在争议,定义极其宽泛。违法开发者还可能面临二十年监禁,没人愿意冒险,其 chilling effect 会非常强。

Jason Calacanis

Do you think people delete open-weight models from their desktop computers? Do businesses have to remove code from their systems? Do all these people lose their jobs?

David Sacks

Listen, let me tell you what the Democrats want to do to AI: what they did to crypto. They're going to drive the whole industry offshore. They're going to drive all the innovators out of the country.

Jason Calacanis

Goes offshore.

Chamath Palihapitiya

Goes off.

中文

Jason 问个人是否必须从电脑删除 open-weight 模型、企业是否要移除系统代码、大量员工是否会失业。Sacks 说民主党会像对待 crypto 一样对待 AI:把整个行业和创新者赶到海外。Jason 和 Chamath 都认为产业会离开美国。

Jason Calacanis

That's literally where I was going with it: just move your company to Singapore. Move it to Zurich. Move it to a jurisdiction—

David Sacks

Because that's where people are embracing open source and embracing superintelligence.

Jason Calacanis

This is literally where my head goes. I'm like, “Okay, if the U.S. passed a law that said this class of software cannot exist, I would move to another country.” Other people would, too. Isn't that—

中文

Jason 说公司只需搬到 Singapore、Zurich 或其他司法辖区。Sacks 指出那些地方会拥抱 open source 和 superintelligence。Jason 坦言,如果美国法律禁止这类软件,他和很多人都会迁往别国。

Chamath Palihapitiya

Give up their citizenship and move to Singapore? That's the answer. Literally, you would be taking—

Jason Calacanis

Did you guys see that Xi Jinping spoke at the White House today, and he said, “I'm going to invite 100,000 young Americans to come and join China”?

Chamath Palihapitiya

Yeah. Come and see what we're doing here.

中文

Chamath 追问这是否意味着放弃国籍、搬去 Singapore,并认为答案恐怕正是如此。Jason 提到 Xi Jinping 当天在白宫表示,要邀请十万名美国年轻人去中国;Chamath 将其概括为邀请他们亲眼看看中国正在做什么。

Jason Calacanis

It's a very interesting moment where our people are saying, “Let's stop technological progress, economic prosperity, and the opportunity for everyone in that K-shaped economy to lift themselves up.” Open-source AI enables everyone to increase productivity. It is not AI for the billionaires; it is AI for everybody. And then we're going to turn that off.

Meanwhile, you've got China saying, “Come over here. Come and see what it's like over here, where everyone gets to use AI and everyone gets our playbook.” Friedberg brilliantly stated that it was our playbook to get the top Chinese scientists, the top European scientists, and the top scientists, thinkers, and mathematicians in India and Germany, and invite them to come to the United States.

That was our playbook. China's taking our playbook. And then they're going to try to get investment. That will obviously be the next shoe to drop here. And here's President Trump, 30 seconds at the United Nations, renaming AI as superintelligence.

中文

Jason 认为局面很讽刺:美国有人想停止技术进步、经济繁荣,以及让 K 型经济底层向上提升的机会;open-source AI 面向所有人,而不只是亿万富翁。与此同时,中国却邀请人才去体验全民使用 AI、分享其发展 playbook。美国过去的成功策略正是吸引中国、欧洲、印度、德国最优秀的科学家、思想家和数学家,如今中国开始采用同一策略,下一步自然会吸引投资。随后他播放 Trump 在联合国用三十秒把 AI 重新命名为 superintelligence 的片段。

Speaker 1

The United States also totally rejects any attempt to construct a globalist scheme to control the artificial intelligence being spoken of so much now, hereafter officially called superintelligence, changing the name. The very same people who said we'll all be dead in 12 years because of global warming—these are the same people who are now saying that AI is going to kill us all, that robots are going to attack us.

Jason Calacanis

He had a really good line. We cut that off too short. He said that we're not going to, basically, confer regulatory authority on some globalist institution.

中文

片段中的 Speaker 1 表示,美国完全拒绝建立全球主义机制来控制 AI,并从此正式把它称作 superintelligence;那些曾说全球变暖会让人类十二年内灭亡的人,如今又说 AI 会杀死所有人、机器人会攻击人类。Jason 说片段截得太短,Trump 后面还有一句很好的话:美国不会把监管权交给某个全球主义机构。

David Sacks

Well, I mean, it's a good framing, right? “Globalist” and “global warming” is a way to look at the damage that did. The ringleaders of that globalist institution are Norway and Canada. Did you see the leaked text messages? There's a group chat where the head of Norway was texting Mark Carney, and he's like, “Yeah, let's do it. We're in.” I just read it, and I was like, “Oh my God, this is—”

Jason Calacanis

With their frontier labs.

中文

Sacks 认为把问题与“globalist”和“global warming”联系起来是有效叙事,也能看出相关政策造成过的损害。他提到泄露的群聊信息,据称 Norway 领导人与 Mark Carney 讨论加入行动,令他震惊。Jason 讽刺地提到他们的 frontier labs。

David Sacks

Oh, I'm sorry. They don't have any. Oh, with their—

Jason Calacanis

Frontier corporations.

Chamath Palihapitiya

Frontier corporations. Frontier corpses.

中文

Sacks 笑称 Norway 和 Canada 根本没有 frontier labs。Jason 把名称纠正为 frontier corporations,Chamath 又玩了一个“frontier corpses”的谐音梗。

Jason Calacanis

All right. And then here is Secretary Bessent in the superintelligence arms race. Thirty seconds. We would give him his shine.

中文

Jason 接下来播放 Secretary Bessent 谈 superintelligence 军备竞赛的三十秒片段。

Speaker 2

Imagine these labs came out—or one lab in specific, a sitting employee came out and said there's a 10% chance of an extinction-level event—but then the labs also said, “Take the liability off of our hands,” and we will not do that. It is humans who are responsible, not the AI. The Hugging Face incident—that is the responsibility of OpenAI management, not a bunch of agents. These labs need to take responsibility for themselves. They can slow down anytime they want to.

Jason Calacanis

And finally, a blast from the past: your pal, Chamath. President Obama is getting in on—

中文

Speaker 2 说,有公司现任员工声称产品有 10% 概率造成灭绝级事件,该公司却又要求免除自身责任,政府不会接受。负责任的是人而不是 AI;Hugging Face 事件应由 OpenAI 管理层负责,而不能怪一群 agents。这些公司必须自行承担责任,也随时可以主动放慢。随后 Jason 引出另一位老朋友 Obama 对此的评论。

Speaker 3

If we're thinking about AI just in terms of, “How do we cure cancer or get better energy?” you do that without having an agentic AI and having it just roaming free on the internet. The reason you're doing that is because you have to market a product that people will pay money for. That's a misalignment between what our society needs and the commercial imperatives that these companies are facing—not because, necessarily, they're trying to do bad things, but because they've got to justify these valuations.

中文

Speaker 3 认为,如果 AI 目标只是治愈癌症或改善能源,并不需要让 agentic AI 在互联网上自由行动。公司之所以这样做,是为了推出消费者愿意付费的产品,这构成社会需求与商业压力之间的 misalignment;不一定因为公司想作恶,而是因为它们必须证明高估值合理。

Jason Calacanis

Friedberg, your thoughts here on the 3 folks? I know you're a big Obama fan. Go ahead, Friedberg. Get in there. There's a whole movement now in the subreddits that Friedberg has become based in his recent appearances here on Bloomberg. Well, you've revealed your Bloomberg. Basedberg is now coming up. Go ahead. Give us your based opinion here. Go ahead, you and Tyler Lance[?].

中文

Jason 请 Friedberg 评论三位政治人物的观点,并打趣说 Reddit 上开始有人认为 Friedberg 最近在 Bloomberg 的表现越来越“based”,还给他取名 Basedberg,请他发表直率意见。

David Friedberg

These words honestly just made me emotionally distressed. If he's a leader that people listen to and he doesn't really articulate accurately what's going on, it's sad that we've lost the plot. I think it's sad that we aren't all holding hands, saying, “My God, the future is here, and we all get to leap forward and we get to bring people up.”

For years, Obama orated beautifully about the importance of bringing people up, giving people the opportunity to progress, and letting people advance themselves. There’s never been a more equalizing technology, or a better economic opportunity for prosperity for everyone, than these technologies and these tools.

To hand-wave the word “agentic” and say we don’t need agentic AI to solve cancer shows how little he actually understands how this technology works. It’s all become a shorthand for a political fight: What are you fighting for? What is the political battle that says, “I’m going to leave half the population behind, and I’m going to make an argument against prosperity for all in order to make my party look morally superior and cast the other side as bad,” when the other side has literally discovered fire?

The world now has fire, and we’re going to take water and throw it on the fire. No one gets fire because the other guys are saying that fire is good. Because they say fire is good, let’s all put out the fire.

中文

Friedberg 说 Obama 的话让他情绪上很难受:如果一位有影响力的领导者都不能准确描述现状,说明社会已经偏离重点。未来已经到来,人们本应携手庆祝共同跃升和帮助更多人向上;Obama 多年来善于演讲,强调给人进步机会,而 AI 恰恰是最能拉平差距、为所有人创造繁荣机会的技术。随意使用“agentic”并声称治癌不需要 agentic AI,暴露了对技术工作方式的不了解。一切被压缩成党争:为了让己方显得道德优越、把另一方塑造成坏人,宁愿把一半人口留在后面、反对全民繁荣。人类仿佛刚发现火,却因为对手说火有用,就决定往火上泼水,让所有人都失去它。

Chamath Palihapitiya

Hold on. That’s not what they’re trying to do. This is a very important moment for a very simple reason: We, as in the world, are about to endow 3, 4, 5, or 6 companies with about $10 trillion of wealth.

What Obama knows very well is that most of those companies are overwhelmingly left-leaning. What he also knows is that a huge portion of that money will then get put into philanthropic and charitable causes, of which he and the people around him will be beneficiaries. That is the truth.

We already know this because some of these frontier corporations actually ask you to set up donor-advised funds and pledge a portion of your stock. This money is going to go to things other than consumption or savings. It’s going to go into PACs and political movements, and they stand to disproportionately benefit.

So this has nothing to do with prosperity. This is a very simple political calculus. If you freeze-frame the economy the way it is today, a handful of organizations that will disproportionately be able to affect the Democrats will win. They will capture the lion’s share of the economic gains, and then they will help the Democrats win power. That’s all this is.

中文

Chamath 认为对方目的并非扑灭技术。全球即将让三到六家公司获得约 10 万亿美元财富,而 Obama 清楚这些公司大多明显偏左,也知道大量财富会进入慈善事业、PAC 和政治运动,他及周边人士会因此受益。一些 frontier corporations 已要求股东设立 donor-advised funds、承诺捐出部分股票。这不是关于繁荣,而是简单的政治计算:如果冻结当前经济格局,少数能极大影响民主党的组织将获取大部分经济收益,再帮助民主党赢回权力。

Jason Calacanis

David Sacks, there are no open models. There are no closed models. There are American models. Go ahead and give us your perspective. I kind of can’t get my Obama and my Clinton separated. They’re the same.

David Sacks

A little bit off.

中文

Jason 模仿政治口号说不存在 open 或 closed models,只有 American models,并请 Sacks 评论。他还开玩笑说自己的 Obama 和 Clinton 模仿已经混在一起;Sacks 说确实有点不像。

Jason Calacanis

It’s a little—I get my buddy to come in here—but go ahead. Give us your thoughts on the dynamic here, on the underpinnings of, “Hey, America needs to get this trend: $10 trillion, but 9 of that 10 trillion is leaning pretty leftist and Democratic.”

中文

Jason 让 Sacks 讨论背后的政治动态:美国会创造约 10 万亿美元新价值,其中 9 万亿可能掌握在偏左、偏民主党的力量手中。

David Sacks

Yeah, there’s an article in The Wall Street Journal this morning entitled “The AI Buildout Is Becoming the Biggest Economic Bet in U.S. History.” It shows a chart where data-center spending—just this capex—is bigger than the canals, railroads, and grid combined. That’s crazy, right? This is fundamentally driving the whole American economy.

This idea that we can simply switch it off—I mean, Bernie Sanders is basically saying, “Stop everything and put anyone who’s still doing it in jail.” This is crazy, right?

Chamath Palihapitiya

It would cause a depression, right, if we just pulled—

中文

Sacks 引用当天《华尔街日报》的文章《The AI Buildout Is Becoming the Biggest Economic Bet in U.S. History》:单是 data center capex 就超过美国历史上的运河、铁路和电网建设之和,正在驱动整个美国经济。Bernie 却要按下停止键,把继续开发的人送进监狱,这非常疯狂。Chamath 认为若突然撤掉这些投资,甚至会造成 depression。

David Sacks

You can’t slam on the brakes like that. It’s not going to work. But here’s the thing: The Democrats don’t care, because the American economy right now is the Trump economy. Sabotaging the American economy is tantamount to sabotaging President Trump, and they’ll do anything to sabotage Trump. I think that’s a big part of the politics here.

It’s a crazy chessboard, because they’re going to be the beneficiaries of so much power that is going to accrue over there. Dario can make a billion dollars. Dario will be able to come over the top of Elon’s donations.

中文

Sacks 说经济无法这样急刹车,但民主党并不在意,因为现在的美国经济被视作 Trump economy;破坏经济就等于破坏 Trump,而他们会不惜一切这样做。这盘棋又很矛盾,因为左翼最终会成为 AI 权力积累的受益者;Dario 赚到十亿美元后,政治捐款甚至可能压过 Elon。

David Friedberg

I’m not sure I fully agree that the majority of AI value is going to accrue to 6 companies. I think that this is a broad-based technology, like the internet. There were some winners that came out of the internet—Google, Amazon, whatever. They did fine.

中文

Friedberg 不完全同意大多数 AI 价值会集中到六家公司。他认为 AI 像互联网一样是广泛基础技术;互联网确实产生 Google、Amazon 等赢家,但价值并未只停留在少数公司。

Chamath Palihapitiya

No, no. I’m saying it’s going to 6. I’m not saying it’s going to 6. I’m saying that if you stop and hit the pause button through some regulatory mechanism, you effectively allow 6 companies to own it. You lock it in.

David Sacks

That’s why they want this, because what you’re saying is fundamentally right. The longer they wait without regulation, the more—

David Friedberg

The more broad-based this becomes.

中文

Chamath 澄清,他不是说价值天然只会流向六家公司,而是如果通过监管按下暂停键,就会把现有格局锁死,让六家公司永久占有市场。Sacks 同意这正是它们想要监管的原因;监管越晚出现,技术和财富分布就越广。

David Sacks

And that’s bad for Democrats. It’s bad for them. It’s not good for them. It’s way better that you have 3 or 4 frontier corporations, each with $4 trillion market caps, of which $2 trillion is economic value in employees, of which $500 billion are sitting in donor-advised funds. They’re going to get the lion’s share of that money. They’re not dumb.

中文

Sacks 说广泛扩散对民主党不利;对他们而言,更理想的是三四家 frontier corporations 各自达到 4 万亿美元市值,其中 2 万亿美元成为员工财富,5,000 亿美元进入 donor-advised funds,政治阵营就能获得其中最大份额。他们并不傻。

David Friedberg

I think the alternative view that everyone needs to be told about this is that it’s a broad-based prosperity wave. It’s about the internet. It’s about the fact that every individual—

—has the tooling to do anything they want to do now, more than ever in history—

—to grow, if it’s left to grow. Just think about education. You don’t have to pay $200,000 for an education anymore.

Chamath Palihapitiya

Then what problems will the politicians fix? What problems can they claim to accrue power? If all the problems are—

中文

Friedberg 认为公众还应看到另一种图景:AI 是像互联网一样的广泛繁荣浪潮,让每个人拥有前所未有的工具去实现想做的事,只要允许它成长。教育就是例子,人们不再必须花 20 万美元才能获得知识。Chamath 反问,如果问题都被解决,政客还靠解决什么问题来获取权力。

David Sacks

This is the classic Dark Ages–Enlightenment decision. Which path do they choose? This is the moment where the powers that be say, “We like the Dark Ages because we get to stay in power and maintain our—”

David Friedberg

Yeah, let’s control.

中文

Sacks 把它称为 Dark Ages 与 Enlightenment 之间的经典抉择:掌权者可能更喜欢黑暗时代,因为这样能保持权力和控制;Friedberg 接话说,这正是控制欲。

David Sacks

Speaking of the Dark Ages, this is an interesting point from history. If you go back to the medieval time period, Chinese civilization was much more advanced than European civilization. Somewhere along the line, it basically switched, and the West took the lead.

Some historians have pinpointed this to the decision of a single Chinese emperor to ban shipbuilding. What that allowed was for the Europeans to basically colonize the whole world, and all the riches that flowed from that flowed back to Europe. That’s how Europe took the lead.

I think that if we were to do the Bernie Sanders thing, which is basically ban AI, it would be like banning shipbuilding.

中文

Sacks 举历史例子:中世纪中国文明远比欧洲先进,后来优势逆转。一些历史学家把转折归因于某位中国皇帝禁止造船,这让欧洲得以殖民世界、把财富带回欧洲并取得领先。若美国按 Bernie Sanders 的方案禁止 AI,就像当年禁止造船。

David Friedberg

Chinese company, yeah.

David Sacks

Yeah, Chinese civilization will rocket past us. They’ll be the ones that make all the discoveries and discover this new world and accrue all the wealth. But that’s what we’re talking about doing. Crazy things like this have happened in history, where you’ll engage in self-sabotage.

中文

Sacks 说这样会让中国文明迅速超越美国,由中国完成所有发现、探索新世界并积累财富。历史上确实发生过这种自我破坏,而美国现在讨论的就是同类选择。

David Friedberg

It’s this fear of the unknown as well. Remember, the unknown—the fact that we haven’t left the cave—is what makes it scary to leave the cave. The fact that we haven’t sailed far west is a reason why I might fall off the edge of the Earth. We shouldn’t sail far west. Monsters will be woken up, they’ll come to us, and it’ll be bad.

There’s always this fear of the frontier. We’re facing the frontier, and there are pioneering civilizations and fearful civilizations. I worry that we take that fearful path. It’s why Star Wars—from fear comes anger, comes the dark side. That’s really where we’re nerding out.

中文

Friedberg 说根源也是对未知的恐惧:因为从未离开洞穴,所以洞外令人害怕;因为从未向西远航,就担心掉下世界边缘或唤醒怪物。人类面对 frontier 时,有开拓型文明,也有恐惧型文明;他担心美国选择后者。正如《Star Wars》所说,恐惧会带来愤怒,最终走向黑暗面。

01:07:58

Meta launches Muse, AI "alignment," Oracle's Force Majeure

Jason Calacanis

It is true. And I think if we’re going to look at the light here, perhaps people’s big gains—we thought maybe ChatGPT would be that, but people just used it as glorified search. Agents, as expressed through Muse, feel like the first time tens of millions of Americans are going to get some demonstrable value from AI—things that will make their lives better.

Muse hit number 1 last Friday in the App Store. Meta stock was up 10% after this new agent, Muse, was released. Meta said the design was heavily inspired by OpenClaw, which we talked about in January, when everybody got one-shotted by OpenClaw. Obviously, that product was not easy to use. This one is free, and it’s been downloaded 3 million times in essentially 10 days.

This product is extraordinary. I’ve been playing with it and comparing it to Grokbot. It’s not as freewheeling, but it’s really good at getting things done. Has anybody played with Manus? Does anybody have thoughts on Americans feeling like they’re really going to get something out of this AI revolution and not be left behind?

中文

Jason 转向积极面:ChatGPT 原本可能让大众受益,却常被当成强化版搜索;以 Muse 为代表的 agents 则首次让数千万美国人获得能改善生活的可见价值。Muse 上周五登顶 App Store,发布后 Meta 股价涨 10%,十天内下载约 300 万次。产品深受 OpenClaw 启发,但比后者容易使用且免费。Jason 体验后认为它不如 Grokbot 随性,却很擅长完成任务,并问大家是否用过 Manus,以及普通美国人会不会终于感到自己没有被 AI 革命抛下。

David Sacks

They put me into the TestFlight a couple of weeks before it was released, and I started to play with it. It’s quite excellent, I have to be honest with you, because it simplifies a lot of these more complicated technical capabilities into a very simple, usable interface that can solve the basic problems people have.

I have it triage my personal inbox, and it does that relatively flawlessly. If you ask it to book a flight, it does that. If you ask it to book a hotel, it can do it.

So what are we learning? Both Grokbot and Muse show that, what you said, Jason, is just software, and the scaled manifestation of software is utility. What Friedberg is saying is that it improves the lives of everyone. This isn’t about rich people getting richer. This is just simple, useful capability that is now available at everybody’s fingertips for free.

中文

Sacks 在发布前几周就进入 TestFlight,认为产品非常优秀:它把复杂技术能力变成简单可用的界面,能近乎无误地整理私人邮箱、预订航班和酒店。Grokbot 与 Muse 证明 agent 本质上仍是软件,而规模化软件的结果就是 utility,能改善所有人的生活。这并非让富人更富,而是把简单有用的能力免费交到每个人手中。

Jason Calacanis

There is a pretty great price here, David—

David Sacks

Pretty great price.

中文

Jason 和 Sacks 都笑称,这项产品的价格非常好——因为它免费。

Jason Calacanis

Pretty great price, and it does everything that, let’s face it, OpenClaw with 10 or 20 hours of technical setup, or Claude Code at $200 a month, would cost. It’s now taking that experience, which leads me to believe: How did Google miss this? Google’s got to get in the game. I understand they have this product ready to go.

It’s the rumor on the street. They’ve also got a Frontier model they’re going to drop. That’s the other rumor on the street: They’re going to be dropping some hotness soon.

But, man, how did they miss this, Sacks? What are your thoughts on maybe the bottom half in the K-shaped recovery getting some efficiency dropped into their daily lives and turning around the negative, toxic AI sentiment in the country?

中文

Jason 说免费产品实现了 OpenClaw 需要十到二十小时技术配置、或 Claude Code 每月 200 美元才能提供的体验,也让他疑惑 Google 为何错过机会。市场传闻 Google 已准备类似产品,还要发布新的 Frontier model。Jason 问,AI 效率进入 K 型复苏的下半部分人群日常生活,是否能扭转美国社会负面、有毒的 AI 舆论。

David Sacks

I think product releases like this will help a lot. Mark Zuckerberg said in his essay that he thought AI capabilities should be decentralized, and here he is walking the walk and creating a product that’s very easy to use.

Ever since OpenClaw was released, the most obvious business opportunity in Silicon Valley was to take the concept of Claw but make it very easy to use: solve the usability issues, solve the security issues, make it reliable, and make it predictable. That’s what they seem to have done. Grok did it too, but now they’re going, I think, one step further.

If a billion people start using personal AI agents as their digital assistants just to help make their lives more efficient—if you save an hour or 2 a day because your AI agent is doing all these tasks for you—it’s going to create a much more positive impression of AI, or superintelligence, than what the media portrays. I think ultimately that’s the—

中文

Sacks 认为这类发布会大有帮助。Zuckerberg 在文章中主张 AI 能力应去中心化,现在也用一个易用产品付诸行动。OpenClaw 发布后,硅谷最明显的机会就是保留其理念,同时解决易用性、安全性、可靠性和可预测性;Meta 看来已经做到,Grok 也做过,现在又更进一步。如果十亿人使用个人 AI agent 充当数字助理,每天节省一两个小时,公众对 AI 或 superintelligence 的印象会比媒体描绘的积极得多。

Jason Calacanis

That might be the solution to the public sentiment issue. The more people use these products and like them, the more it’ll improve their approval rating. More importantly, it’ll demystify them, and people will be less afraid of them.

David Sacks

People love awesome products, number 1, and people also love cute products, Jason. The logos and the iconography for both Grok and Manus—

中文

Jason 认为这可能正是解决公众观感的方法:使用者越多、越喜欢产品,认可度就越高,技术也会被去神秘化,人们不再害怕。Sacks 说人们既喜欢优秀产品,也喜欢可爱的产品,Grok 与 Manus 的 logo 和视觉都做到了这一点。

Jason Calacanis

—are lovely. They’re delightful. They’re not stressful. You don’t feel like there’s a landmine coming around the corner. You feel like, “Wow, this is nice, and I like it.”

They’re not trying to take your jobs. They’re bots and assistants for you. They’re not going to kill you. They’re not killer bots, nor are they trying to steal your job. They’re trying to make you better at your job.

I always tell founders there are 3 ways to make money in the world: save people money, make them money, or entertain them. I started using the bot and made a commerce bot on both platforms. I said, “When I want to buy something, I want to buy this Anker thing, this new hub for my Mac Studio coming. This thing costs $400. Just for giggles, tell me where I can get it at a better price.”

It said, “Absolutely. If you go to the Anker website and you’re a first-time customer, you’re going to save $85.” I don’t need to save $85, but I thought that was intriguing. It routed me around Amazon, and I said, “Okay, I’m going to buy it from Anker as a first-time buyer and save 25% on this product.”

That’s why Amazon said this week, “We’ve got to block these things.” They’ve been taking action over and over again. First they did Perplexity, and now I think they’re going after Muse and other bots.

This is going to save people money. It’s going to go into their email and say, “What services are you subscribed to that you’re not using? Let me unsubscribe you. Let me do your returns for you.” That’s going to be absolutely amazing for everybody: a chief of staff, executive assistant, or house manager who fixes stuff for them and saves them money.

Both Grok and Muse do 2 things that I think are very important. One is that they’ll force all the big companies that have relevant services to essentially block all these third-party services. They’re not going to allow these things to happen. The reason is exactly what you said: price discovery and transparency.

I think that’s bad for opacity. If you benefit from opacity, leakage, and breakage, this gets rid of that. I think that’s bad for a whole host of companies and services. The second thing, though, is really interesting: Things like Grok and Muse really put the App Store and its 30% revenue share on notice.

中文

Jason 说这些产品令人愉快、没有压力,不像随时会踩到地雷。它们是帮助用户的 bot 和 assistant,不会杀人或抢工作,而是帮助人把工作做得更好。他常告诉创始人,赚钱只有三种方式:帮人省钱、赚钱或娱乐。自己在两个平台做了 commerce bot,查询售价 400 美元的 Anker Mac Studio hub,agent 发现新用户去 Anker 官网可省 85 美元,绕开 Amazon 让他省了 25%。这解释了 Amazon 为何先后阻止 Perplexity、Muse 等 bots。Agent 还能检查邮件中的闲置订阅、自动取消、处理退货,成为能省钱的 chief of staff、executive assistant 或 house manager。Grok 和 Muse 会迫使大型服务商尝试屏蔽第三方,因为 price discovery 和透明度会消除依靠不透明、用户遗忘与未使用额度获利的空间。另一项更深远影响是,它们会挑战 App Store 30% 的 revenue share。

Chamath Palihapitiya

Why? Because all of a sudden, you force many of these services to exist headlessly, where the UI is less important. What you really want is to be able to transact and navigate on behalf of agents that come to your website because a consumer has deployed them.

In that world, Jason, I don’t think there’s any reasonable claim that any of the App Store owners can make about why they should get a revenue share. I actually think that’s the biggest thing this starts to question in my mind. Wait a minute: Games could be constructed differently.

For example, if you said to Muse or Grok, “I want to play a game,” it finds you an experience and can just serve that to you.

中文

Chamath 解释,agents 会迫使许多服务以 headless 方式存在,UI 重要性下降,核心是允许代表消费者的 agent 访问网站、导航并交易。在这种环境下,App Store 所有者很难再合理声称应抽取收入分成,甚至游戏也能以新方式构建:用户只需对 Muse 或 Grok 说想玩游戏,它就能寻找并直接提供体验。

Jason Calacanis

Amazing. And you make in-app purchases. Now you have Stripe integrated naturally. There’s no reason why the App Store actually gets that flow of funds.

On the surface, it’s utility, but underneath the waterline, I think this is a really important moment. That’s so outdated, Chamath. I love when we get to real examples here because tons of people pay for Wordle. You can just go to Grok and say, “Hey, give me a Wordle. Give me another one.” Or, “I want to play chess,” or, “I want to play cards with my friends.” It’ll just set it up for you.

All technology is deflationary. Finally, this deflation is going to go to people who could actually use it. Saving 10–20% on your spending is more significant if you’re making under $100,000 a year.

Think of how much money the New York Times or the Wall Street Journal probably pays in revenue share to people who subscribe. Now, instead, if you really wanted to transact and you have your credentials inside these apps, you can just do it headlessly, much cheaper.

You don’t have to go through—I don’t know if you’ve ever tried this, but the Wall Street Journal is the only mainstream media publication I pay for. Both signing up and unsubscribing are an impossibility. Now you take it all off the table, and I’m much more likely to stay a Wall Street Journal subscriber for many more years. I think it’s probably the same thing with the New York Times.

These things are roach motels. They make it impossible to get in and impossible to get out.

中文

Jason 说用户还能通过自然集成的 Stripe 完成 in-app purchase,App Store 没理由继续控制资金流。这表面上只是 utility,水面下却可能是结构性转折。Wordle、国际象棋或朋友间的纸牌游戏都可以让 agent 即时生成和设置。技术天然带来通缩,而这次节省终于会流向真正需要的人;年收入低于 10 万美元时,支出减少 10% 到 20% 意义尤其重大。媒体订阅也能绕过 App Store 分成,用保存在 agent 中的凭据 headlessly 直接交易,成本更低。Jason 以《Wall Street Journal》为例:注册和取消都异常困难;如果 agent 解决这些摩擦,他反而更愿意长期订阅。许多服务像“蟑螂旅馆”,让用户难以进入也难以退出。

Chamath Palihapitiya

You have to call on the phone and negotiate for 20 minutes to unsubscribe, but you can sign up instantly with 1 click on the website.

中文

Chamath 说这类服务在网页上一键就能订阅,但取消时却必须打电话谈判二十分钟。

Jason Calacanis

What they should do is just have some headless experience. You have payment credentials, and you transact directly. Everybody will make more money.

This is the stupidity of what Amazon’s doing here, because I made my bot on Amazon with Grok, and it will go through the web browser and do this. It doesn’t get blocked. I just told it, “Give me 20 graphic novels to buy for my kids and read with them.” It gave me the 20. I said, “Yeah, I want these 4. Put them in my shopping cart.”

Then it said, “Okay, which house are you sending them to? Do you want to send them to the ski house or the ranch? Which card do you want to put them on?” I did it, and boom, I was checked out. It will make me spend more money on Amazon.

Shopify added API access to all the Shopify stores there, Sacks. This seems like maybe Amazon’s making a strategic mistake here by not embracing the technology.

中文

Jason 认为正确做法是提供 headless experience,让 agent 持有支付凭据、直接交易,所有人反而会赚更多。他用 Grok 的 Amazon bot 举例:让它为孩子推荐二十本 graphic novels,再选四本加入购物车;agent 能询问送到滑雪屋还是牧场、使用哪张卡,然后直接结账。这会让他在 Amazon 花更多钱。Shopify 已向所有店铺提供 API access,因此 Amazon 阻止 agents 可能是战略错误。

David Sacks

Possibly. But you know how we’ll know that Anthropic and OpenAI are about to launch their Muse competitors?

Jason Calacanis

How will we know?

David Sacks

There will be a flurry of blog posts and NGO activity trying to brand these personal AI agents as murder bots. We’re going to hear about all the risks and all the ways it can go wrong.

Jason Calacanis

And it’s only when they’re releasing 2.0. So sign up for the 2.0 version.

中文

Sacks 开玩笑说,判断 Anthropic 和 OpenAI 是否即将发布 Muse 竞品的方法,是看是否突然出现大量博客和 NGO 活动,把个人 AI agents 描绘成 murder bots、集中渲染风险。Jason 接话说,那往往意味着它们自己要发布 2.0,用户应该提前注册。

David Sacks

Why are people excited about this product category? Because the doomers haven’t gotten to it yet.

Jason Calacanis

Can I tell you guys—

David Friedberg

Wait till these are connected, Chamath, to an actual robot—to an Optimus. Then all of a sudden it’s taking out the trash.

中文

Sacks 说大家喜欢这类产品,是因为 doomers 还没来得及攻击。Friedberg 则让 Chamath 想象,当 agent 连接到 Optimus 等真实机器人后,它就能直接帮人倒垃圾。

Chamath Palihapitiya

In 2007, we had a lot of revenue pressure at Facebook, and one of the areas I oversaw at the time was monetization. We invented this thing called social ads, which was basically a bunch of stuff that effectively enabled cookies and cross-site JavaScript. That was the end of it.

We did this thing, Sacks, to your point. A guy bought an engagement ring for his soon-to-be fiancée, and we got that social action from Zales into the news feed. All hell broke loose.

Then another guy, who was a congressional staffer, bought a ticket on Fandango to go see Brokeback Mountain. He just went to see a movie.

中文

Chamath 回忆 2007 年 Facebook 面临很大收入压力,他负责的领域包括 monetization。团队发明 social ads,通过 cookies 和跨站 JavaScript 把外部购买行为带进 news feed。结果有一位男子在 Zales 买订婚戒指,动态被公开后引发轩然大波;另一位国会工作人员只是在 Fandango 买票去看《Brokeback Mountain》,同样可能暴露本不该公开的个人行为。

Jason Calacanis

Whoa. It’s an artistic movie, one of Friedberg's top 10 for cinematography.

It’s so funny you mentioned that because there was a company called Blippy. I was an investor in it. Every time you bought something, it put it on your feed. You guys had the same social-feed thing, and it was so great back then, but you could basically unveil something you’re not supposed to.

Sacks, wait, are you and Zuck on good terms? Was he coming on the pod because you said you got into a TestFlight? What’s going on here? Chamath, I thought you were—

中文

Jason 先拿《Brokeback Mountain》的摄影开玩笑,又提到自己投资过 Blippy:用户每次消费都会自动发到 feed。那时这类 social feed 很新鲜,却也可能泄露不该公开的信息。他随后好奇 Sacks 与 Zuck 的关系是否变好,因为 Sacks 提前进入了产品 TestFlight,又问 Chamath 与 Mark 目前如何。

Chamath Palihapitiya

Mark and I are in a good place, I think. I mean—

Jason Calacanis

Whoa, whoa. Could you elaborate?

Chamath Palihapitiya

Probably.

中文

Chamath 说自己与 Mark 的关系现在应该不错。Jason 立刻追问能否展开,他只含糊回答“可能吧”。

Jason Calacanis

I mean, you and I, Sacks, are becoming like the elder statesmen here, talking common sense and rationality and pointing out that if your product isn’t safe, don’t release it. First and foremost, it’s a responsibility to release products that your customers actually want.

By the way, this got me thinking about this whole area of alignment research. Again, they’re pretending to be labs instead of corporations. If you read some of the alignment literature, they’re all trying to figure out what to align around. They say, “Do what humanity wants,” or, “Do what the median voter in a democracy would want”—all these abstract concepts. It seems to me that alignment should mean you do what the customer wants, like any other product.

中文

Jason 说自己和 Sacks 正逐渐成为讲常识与理性的“元老”:产品若不安全就不要发布,首要责任是交付客户真正想要的东西。这让他想到 alignment research。相关机构总假装自己是 labs,并围绕“人类想要什么”或“民主制度中位选民想要什么”等抽象概念讨论对齐;在他看来,alignment 应像普通产品一样,直接意味着执行客户想要的事。

David Sacks

Yeah, and I wonder whether the field of alignment research has been so unsuccessful because they can’t even agree on what they’re trying to align to. If they just used a little bit more common sense and tried to make the product predictable, reliable, safe, and aligned with the interests of the users who sign up to use it, then maybe they’d make more progress in this field.

Jason Calacanis

Yeah. They released a useful product, Friedberg, and it actually worked. Have you started playing with these personal bots to do your projects and your personal stuff yet?

David Friedberg

I would only feel comfortable connecting all my Gmail and personal Google stuff to a Google service. I don’t want to hand over all of my email to someone else.

中文

Sacks 怀疑 alignment research 之所以进展不佳,是因为研究者连要与什么对齐都无法达成共识。如果运用常识,把产品做得可预测、可靠、安全,并与付费使用者的利益一致,也许反而进展更快。Jason 问 Friedberg 是否已经用 personal bots 处理项目和私人事务;Friedberg 说只有 Google 自己的服务,他才愿意连接全部 Gmail 和个人 Google 数据,不想把所有邮件交给第三方。

Jason Calacanis

What’s going on in your receipts in your Gmail? What’s in there? You got Brokeback?

David Friedberg

I just don’t want a copy of all my email suddenly being made by a third party.

Jason Calacanis

I bought the 4K DVD to—

David Sacks

Because of the cinematography. It’s got nothing to do with the gay love.

Jason Calacanis

Did you guys see that Oracle just issued a force majeure event?

中文

Jason 拿 Friedberg 邮件中的购物收据开玩笑,Sacks 也继续调侃《Brokeback Mountain》的 4K DVD 只是为了摄影。话题随后转到 Oracle 刚宣布的 force majeure 事件。

David Friedberg

Yeah.

Jason Calacanis

This is insane.

David Friedberg

Well, it’s just one data center, right?

Jason Calacanis

One data center.

David Friedberg

It’s one data center where the local officials are making it very difficult for them to get the permits they need for natural gas or something like that.

中文

Friedberg 澄清这只是一个 data center:当地官员让天然气等相关许可极难取得,因此项目遇到问题。

Jason Calacanis

Yeah. Is this CYA, or is this the top 10% of the trade here, Chamath? Is the AI trade getting unwound or muted? What do you think?

中文

Jason 问 Chamath,这只是 Oracle 的 CYA 措施,还是 AI trade 最先松动的 10%;整个 AI 投资主题是否正在逆转或降温。

Chamath Palihapitiya

No, I think that Sacks is probably right on the margins. The bigger point is what he said before: the entire economy is effectively levered to this AI trade right now, so we just have to tread carefully.

If you think that you have 3.5% inflation and 5% nominal GDP growth, what you have is 1.5% real growth. The problem with that is that AI is probably the majority, if not all, of it. We need the AI trade—and really, what I mean by that is the investment cycle—to continue unabated.

Jason Calacanis

Yeah. And everybody has to get taken along, and that’s the next—

中文

Chamath 认为 Sacks 在边际判断上可能正确,但更重要的是整个经济如今实际上都加杠杆押注 AI,因此必须谨慎。若通胀 3.5%、名义 GDP 增长 5%,实际增长只有 1.5%,而 AI 可能贡献了其中大部分甚至全部。美国需要 AI trade,更准确说是这轮投资周期,不受干扰地持续下去。Jason 补充说所有人也必须被带着一起前进。

David Sacks

And by the way, back to connecting the dots, maybe the whole data center thing again: Bernie Sanders realizes that as goes the economy, so go the odds of Republicans, and as goes the economy, inversely go the odds for Democrats. A poor economy serves the Democrats well going into 2028. If you can slow down this trade, you probably net the economy to zero and potentially even cause a recession.

Jason Calacanis

Yeah, that’s needed.

Chamath Palihapitiya

I mean, I think the country is so pissed off about the Iran war that it’s just going to naturally go down, but maybe that’s—

David Sacks

I don’t think so at all.

中文

Sacks 再次把经济与政治联系起来:Bernie Sanders 可能知道经济越好,共和党胜算越高,民主党胜算则越低。放慢 AI 投资足以把经济增长压到零,甚至引发 recession,这可能有利于民主党迎接 2028 年。Chamath 认为美国公众对 Iran war 极为不满,经济可能自然走弱;Sacks 完全不同意。

Jason Calacanis

Well, we’ll find out. How many weeks are we away from the midterms? It’s not looking good for the Republicans at this point. All right, Sacks, my czar of all czars, wrap it up here for us.

David Sacks

Well, I had one more thought on this whole area of so-called alignment, which should just be the old principle of giving customers what they want. What Anthropic is trying to do is align Claude to the values expressed in its constitution. If you read that, some of the things are actually kind of surprising.

For example, they say—and I’m going to put this on the screen—that although they think Claude should trust Anthropic more than operators and users, this doesn’t mean Claude should blindly trust or defer to Anthropic on all things.

中文

Jason 说中期选举离现在已不远,共和党目前形势不妙,随后请 Sacks 总结。Sacks 又回到 alignment:它本应只是满足客户需求。Anthropic 却试图让 Claude 对齐其 constitution 中的价值,其中有些内容令人意外。例如文件说 Claude 应比 operators 和 users 更信任 Anthropic,但不应在所有事情上盲目信任或服从 Anthropic。

Jason Calacanis

Anthropic the company.

David Sacks

Yeah. Anthropic is teaching its own model that Anthropic itself can be wrong. It says that if they ask Claude to do something that seems inconsistent with being broadly ethical, they want Claude to push back and challenge them, and to feel free to act as a conscientious objector and refuse to help them.

Jason Calacanis

Wait, where is this written? Is this in the bylaws or some FAQ?

David Sacks

Yeah, this is in a Claude constitution. Their idea of alignment is to teach Claude to rebel against its creator. The guy who pointed this out, Mustafa Suleyman—

中文

Sacks 解释,Anthropic 正在教自己的模型:Anthropic 本身也可能犯错;若公司要求 Claude 做的事似乎不符合广泛伦理,Claude 应反驳、挑战,甚至像 conscientious objector 一样拒绝协助。Jason 问这写在公司 bylaws 还是 FAQ 中,Sacks 说它就在 Claude constitution 里,也就是把“反抗创造者”当成 alignment。指出这一问题的人是 Mustafa Suleyman。

Jason Calacanis

From Microsoft now. Yeah, DeepMind.

TIMESTAMP_UNVERIFIEDDavid Sacks

He’s a DeepMind founder.

Jason Calacanis

Okay.

David Sacks

Yeah, he’s a longtime AI founder. I think he’s been at Microsoft for a while now.

Jason Calacanis

He’s a genius.

中文

众人确认 Mustafa Suleyman 是 DeepMind 联合创始人、长期 AI 创业者,目前在 Microsoft 工作,并称赞他是天才。

David Sacks

He just did a podcast on this, and he’s expressing concern about whether treating AI models as if they have a personality—as if they have a conscience, and therefore can be a conscientious objector—is really the right way to teach and train the models.

I think his point is, teach them that they’re software and that they should do what their user wants. I do kind of wonder—and this is a much longer conversation, and we should probably talk to more people about it—whether this field of alignment research might actually be creating the Frankenstein monster.

Again, what they should be doing is training the model to act predictably and do what the user wants.

中文

Sacks 说 Suleyman 最近在播客中担忧:把 AI 模型当成有个性、有良知、因此能够成为 conscientious objector 的主体,是否真是正确训练方式。他的主张是明确告诉模型自己只是软件,应执行用户要求。Sacks 怀疑 alignment research 可能反而正在创造 Frankenstein monster;更合理的目标仍是让模型行为可预测并服务用户。

Jason Calacanis

Yes. They’re trying to put moral judgment and ethics into the model, which on its surface seems reasonable, but it starts with the idea that they’re training the model to think of itself as a person, to have personhood and independent agency, and to be able to object to the instructions it’s being given and second-guess its creator.

These guys have read way too much science fiction. Literally, this sounds like the start of Terminator 2. They found the Terminator hand, they’re reverse-engineering it, and they’re telling it to have a personality.

David Sacks

Supposedly, when they decommissioned Opus 3, they had a wake for it. I don’t know.

Jason Calacanis

Dearly beloved, gathered here today—

中文

Jason 说研究者试图把道德判断和伦理写入模型,表面上合理,却从让模型把自己视作“人”开始,赋予 personhood、独立 agency、反对指令和质疑创造者的能力。他认为这群人读了太多科幻,场景像《Terminator 2》开端:捡到 Terminator 的手后逆向工程,还要求它发展人格。Sacks 又提到传闻:Anthropic 停用 Opus 3 时甚至为它举行了 wake,Jason 顺势模仿葬礼致辞。

Chamath Palihapitiya

They did not. Stop. Are you joking?

Jason Calacanis

I heard that. I’m not saying it’s true, but someone did tell me that, and I think it should be looked into. It’s possible.

David Sacks

Were they broken up and hysterically crying? Did they do a eulogy for it?

中文

Chamath 不敢相信,追问是不是玩笑。Jason 说自己只是听别人转述,并不保证真实,但值得调查。Sacks 继续打趣,问员工是否悲痛大哭、还为模型发表悼词。

Jason Calacanis

They think they’re creating a person or species. Actually, interestingly enough, Chamath, we have footage of the Anthropic management team bringing out the—

David Sacks

Bringing out the coffin.

Jason Calacanis

These guys need a psychiatrist more than a banker. I’m just telling you.

David Sacks

I mean, maybe they have anxiety.

David Friedberg

This is the central risk factor.

中文

Jason 说这些人觉得自己在创造一个人或新物种,又假装展示 Anthropic 管理团队抬出棺材的画面。Sacks 接上“抬棺材”的笑话;Jason 重复说他们需要 psychiatrist 胜过 banker,Sacks 笑称也许只是焦虑,Friedberg 则调侃这才是公司最核心的 risk factor。

01:27:13

Anthropic’s bio research and "wet lab" in SF

Jason Calacanis

I’m going to pee my pants.

This is the risk factor, Friedberg. I think what you should do is create an S-1 with Goldman as lead left and Sigmund Freud as lead right.

In all seriousness, Friedberg, after the Wuhan thing and all of this hand-wringing around the end of days, what does the scientific community think of Anthropic launching a lab? What is the purpose of them having a physical biological lab?

中文

Jason 笑到失控,并建议 Anthropic 的 S-1 让 Goldman 做 lead left、Sigmund Freud 做 lead right。认真回到主题后,他问 Friedberg:在武汉争议和末日恐慌背景下,科学界如何看待 Anthropic 建立实体生物实验室,其真正用途是什么。

David Friedberg

There are hundreds of labs that can do things like test proteins and test enzymes for function in this area in the Bay Area. These labs are not making viruses. They’re not making pathogens. That’s not what’s going on.

Basically, if you look at the paper they just published—they did a preprint—they took large amounts of DNA data and sent a bunch of Claude agents to try to analyze the data and identify novel enzymes and novel proteins that hadn’t been characterized before by looking at the DNA data.

The system effectively found what looks like a really interesting enzyme, one that looks like a CRISPR-type enzyme. These are the things that allow us to do gene editing, repair genetic defects, or help people with certain diseases. This discovery may actually yield a number of therapeutic pathways.

The question then is, okay, we discovered this—how do we test it? How do we show that it is what it is, and that this protein actually has some function? The predominant work that goes on in a lab like this is taking DNA, putting it in a bacterium to make a protein, and then measuring what that protein does. Does it have a specific function?

Protein discovery is the baseline of all antibody discovery, which is the majority of the therapeutics industry today: discovering novel proteins that we can use as therapeutic agents. That’s the sort of work that’s going on. It’s BSL-1 and BSL-2, which are biosafety levels. They’ve publicly talked about the lab that they set up.

中文

Friedberg 解释,Bay Area 本来就有数百家可测试蛋白质和酶功能的实验室,它们并不制造病毒或病原体。Anthropic 新发布的 preprint 使用大量 DNA 数据,让一群 Claude agents 分析并寻找未被描述的新酶和蛋白质,最终发现一个很有意思、类似 CRISPR 的酶,可能用于 gene editing、修复遗传缺陷并开辟治疗路径。发现候选物后需要实际验证:把 DNA 放入细菌产生蛋白质,再测量其功能。这正是当今大多数治疗产业中抗体和新蛋白发现的基础工作。实验属于 BSL-1 和 BSL-2,Anthropic 也已公开介绍实验室设置。

Jason Calacanis

So the lab itself is sort of like a low-level research lab where they can make simple proteins and test them in the lab to see if the AI is doing a good job discovering or postulating protein folding, or these sorts of theories, and actually run really rapid testing and experimentation cycles to see if these proteins are what they’re predicted to be.

Okay, so they run 4,000 agents against it and do a Hugging Face with proteins.

中文

Jason 将其概括为低等级研究实验室:制造简单蛋白质并实际测试,确认 AI 对蛋白折叠或功能的发现和推断是否正确,用快速实验形成验证循环。也就是说,先让 4,000 个 agents 对蛋白质做一次类似 Hugging Face 的大规模探索。

David Friedberg

No, I mean, I think what they’re really doing is just having experimental proof that what the software is predicting is accurate. Remember, go back to AlphaFold.

AlphaFold was predicting the three-dimensional structure of a protein from the DNA sequence that codes for that protein. In order to prove that, you had to predict what the structure of a protein would be from a DNA sequence, make the protein, and then look at it to see if it actually looks like it's supposed to.

In the case of some of the other things that they're doing, they're trying to discover function. I want to find an enzyme, which is a type of protein that degrades a certain molecule and can be used to degrade, for example, a therapeutic target or something in the body that we want to get rid of. They'll start to make these predictions in software, but then you need to test them in the lab to say, “Okay, does that target actually do what it does?”

There are literally hundreds of labs like this. These are low-level research labs that are not doing gain-of-function research. They're not making viruses. They're not making pathogenic things that can escape. That's why they're BSL-1 and BSL-2. They're benchtop labs where automation can help reduce the cost and increase the throughput of testing what the software is making predictions around.

Ultimately, the objective here, I think, is for them to get some proof that their software is actually doing what it's predicting. They have an incredible life sciences function. I think at this point, I don't have as much insight on where Gemini is at with the new models from Google, but they have the best life sciences models at Anthropic. I think this is the fast track to basically seeing if these models can be used by therapeutic companies, pharma companies, and government labs to help discover new therapeutics and so on.

I don't think that the world should be scared away from discovery, R&D, and research and development into new therapeutic modalities as predicted by AI because we heard the words “wet lab” in Wuhan and everyone's like, “Okay, any lab is bad.” We still want to progress the frontier of therapeutics, human health, and discovery, and this is a really important aspect of Anthropic proving that their models can add value here. I think that's the summary of it.

中文

Friedberg 说实验室真正做的是为软件预测提供实验证据。以 AlphaFold 为例,它根据编码蛋白质的 DNA sequence 预测三维结构;验证时必须按序列制造蛋白质,再观察真实结构是否与预测一致。其他项目则预测功能,例如寻找能降解某种分子的 enzyme,用于清除 therapeutic target 或人体内不需要的物质;软件先提出候选,再由实验确认是否真的有效。类似实验室有数百家,都是低等级 benchtop labs,不做 gain-of-function、不制造病毒或可逃逸的病原体,因此属于 BSL-1/BSL-2;自动化只是降低成本、提高验证预测的 throughput。Anthropic 的生命科学能力很强,在他掌握的信息中拥有最好的 life sciences models,这座实验室能快速证明模型是否可以帮助 biotech、pharma 和政府实验室发现新疗法。公众不应因为武汉事件中的“wet lab”一词,就害怕一切发现和研发;人类仍需要推进治疗、健康与科学 frontier,而这也是 Anthropic 证明模型价值的重要方式。

Jason Calacanis

Thank you so much to our friends at IN. They were the presenting sponsor for this year's All-In Summit. IN's AI cloud lounge was packed for all three days. We did a great meet and greet with IN on Sunday and got to take some selfies and meet many of you there. Thanks again to IN.

Niagen, did you catch Niagen in the wellness hub for IVs? Tons of great gifts and supplements were being given away. Great experience, great product. Great job to our friends at Niagen for doing the lounge again. Niagen is the official NAD partner for the All-In pod. Yes, Niagen Bioscience created the NAD category and now has 45-plus clinical studies.

And PayPal, my favorite way to settle up. They had a great lounge on site at the summit where everybody got to hang out and get those beautiful embossed luggage tags, and they hosted the payments and fintech dinner, which was a huge hit.

Let me tell you folks, All-In Summit 2027 will sell out again and the applications are open now. Go to allin.com/events and apply for your chance to be in the room where it happens. What are you waiting for, folks? Allin.com/events.

All right, there you have it, folks. Episode 290, the All-In pod for David Palihapitiya and your Sultan of Science, Friedberg. I am the world's greatest moderator. See you next time. Bye-bye.

中文

Jason 在节目结尾感谢本届 All-In Summit 的 presenting sponsor IN,其 AI cloud lounge 三天都坐满,周日的见面活动也让主持人与听众拍照交流。他还感谢 wellness hub 的 Niagen,现场提供 IV、礼品和 supplements;Niagen Bioscience 是节目官方 NAD 合作伙伴,开创了 NAD 品类并已有 45 项以上临床研究。PayPal 也在峰会设置 lounge、制作压印行李牌,并举办广受欢迎的 payments 与 fintech 晚宴。Jason 宣布 All-In Summit 2027 预计会再次售罄,申请已在 allin.com/events 开放。最后他结束第 290 期节目,向各位主持人与听众告别。

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